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IRCT20170429033680N8 IRCT 2018-08-11 Mashhad University of Medical Sciences Dexmedetomedin Infusion on Reducing Pain The Effect of Dexmedetomedin Infusion on Reducing Pain After Open Kidney Surgery 2017-10-23 anticipated 33 Complete https://irct.ir/trial/28675 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The envelope method is that the envelopes are prepared and printed by a member of the research team and random numbers with the help of the Randomaize.com site and inside the envelope. The door packs will be closed and its contents are not visible from the outside. Then, the purpose of the study is explained to the person who described the conditions, and the person, if desired, signs the informed consent form and removes an envelope, then opens it and, based on the contents of the envelope, enters into the intervention or control group, Blinding description: Participants and researcher are not aware of the type of intervention.The trial was planned in such a way that neither the subjects nor the observers (researchers) know who the group is. N/A Kidney surgery. Intervention 1: Intervention group: Infusion of a dose of 200 micrograms (2 cc) of dexmedmodine was done ones before surgery. Intervention 2: Control group: infusion of 50 cc normal salinewas done ones before surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Mohsen Saber Moghadam Ranjbar
Department of Anesthesiology, Imam Reza (AS) Hospital, Taghiabad Square
Mashhad Iran (Islamic Republic of) 9137913316 +98 518022711 sabermoghaddamm@mums.ac.ir Mashhad University of Medical Sciences scientific Mohsen Saber Moghadam Ranjbar
Department of Anesthesiology, Imam Reza (AS) Hospital, Taghiabad Square
Mashhad Iran (Islamic Republic of) 9137913316 +98 518022711 sabermoghaddamm@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Candidate for open-renal surgery consenting to participate in the study age 18-65 years ASA class 1 and 2 BMI more than 30 have not allergy to the drug no addiction to drug or alcohol not taking benzodiazepines permanently 18 years 65 years Both Systolic blood pressure lower than 100 heart rate less than 60 before the injection Hypotension or heart rate decrease by more than 30% at baseline or during the injection History of psychological illness Use of any analgesic drug before operation Needing to use an additional dose of opiates of more than 20% of the standardized value in the study during anesthesia Be longer surgery for any reason failure to do or complete the surgery at any stage for any reason N18 Chronic kidney disease (CKD) Treatment - Drugs Placebo Intervention group: Infusion of a dose of 200 micrograms (2 cc) of dexmedmodine was done ones before surgery. Control group: infusion of 50 cc normal salinewas done ones before surgery Analgesia. Timepoint: after surgery. Method of measurement: VAS scale. Vice chancellor for research, Mashhad University of Medical Sciences Approved 2018-06-22 Ethics committee of Mashhad University of Medical sciences Mashhad University of Medical Sciences; International Offic Administration Center(Qoreishi Building) ; Daneshgah St., Mashhad Mashhad Mashhad Razavi Khorasan Iran (Islamic Republic of)