IRCT20171217037917N1 IRCT 2018-10-30 Tehran University of Medical Sciences The Effect of NLP Individual Psychotherapy On The Reduction Of Symptom Of Depression, Anxiety, Stress and Improving Quality of Life and Control of proceeding Disease on RRMS Patients Evaluation of effectiveness of Neuro Linguistic Programming individual treatment on depression, anxiety, stress, quality of life and the course and severity of the disease in patients with relapsing-remitting multiple-sclerosis (RRMS): a Randomized Clinical Trial 2018-02-20 anticipated 60 Complete https://irct.ir/trial/28711 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization: After announcement and filling the demographic forms, considering the include and exclude criteria and initial scores in Depression, Anxiety, Stress, Quality of Life and Course of the MS Disease, a total of 60 patients were selected according to a randomized table. Based on the random number table, 30 subjects were divided into two groups: 30 for control and 30 for test. N/A Condition 1: Multiple sclerosis. Condition 2: Anxiety. Condition 3: Depression. Condition 4: Stress. Intervention 1: Experimental or intervention group: 30 patients, One hour individual therapy sessions, intervention: Neuro Linguistic Programming Therapy, 45 sessions: first 16 sessions are weekly, 18 sessions are twice a month and 11 sessions are monthly basis. The therapist's team consists of two masters of Neuro Linguistic Programming, evaluator team who examine the initial implications consist of a psychologist and a psychiatrist and a neurologist. Intervention 2: Control group: 30 patients, without any intervention and with routine care, evaluator team who examine the initial implications consist of a psychologist and a psychiatrist and a neurologist (MS fellowship). No - There is not a plan to make this available Justification or reason for not sharing IPD is due to ethics codes for psychotherapists and counselors