IRCT20180101038178N1 IRCT 2018-02-17 Shahed University Comparing the effect of cryotherapy and acupressure on pain intensity of arteriovenous fistula cannulation in female patients undergoing hemodialysis Comparing the effect of cryotherapy and acupressure on pain intensity of arteriovenous fistula cannulation in female patients undergoing hemodialysis 2017-02-16 anticipated 42 Complete https://irct.ir/trial/28860 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Supportive. N/A Hemodialysis, Arteriovenous Fistula, Pain. Intervention 1: Intervention group: No intervention- The first stage of the study without any intervention after the needle was inserted into the fistula, the patient's pain was measured using a numerical instrument of pain. Intervention 2: Cryotherapy intervention: The researcher put a piece of ice inside a gauze (because the ice melts in the gauze later), and then placed inside the nylon and set on the Hugo point (between thumb and pointing finger) in thepatient's hand no fistula and rubbed the place from the 10 minutes (2 minutes rubbing and 15 seconds rest) before the needle was inserted into the arteriovenous fistula. Then the fistula area was well disinfected and the needle inserted into the fistula by the nurse. Immediately after insertion of the needle and fixing it, the patients' pain was measured using a numerical instrument of pain by an individual who was not aware of the type of intervention. Intervention 3: Acupressure intervention: The researcher carried out using the thumb of the hand in a diagonal direction on the Hugo point (between thumb and pointing finger in the patient's hand no fistula ) 10 minutes before insertion of the needle, alternately (2 minutes massage, medium pressure (not too intense or very mild), and 15 seconds rest ). Then , the nurse inserted needles into the fistula and fixed it, after that the number of pain was measured by a person who was not aware of the type of intervention. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.