<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20180113038343N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2018-02-19</date_registration>
      <primary_sponsor>Islamic Azad University of Neyshabur</primary_sponsor>
      <public_title>Effect of resistance training in cardiac rehabilitation</public_title>
      <acronym></acronym>
      <scientific_title>Effect of eight weeks resistance training in land and water on lipid profile change and the blood mononuclear cells PPAR-ɑ and ABCG8 gene expression in middle-aged women after Coronary Artery Bypass Grafting</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2018-01-25</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>30</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/28957</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Following a random screening, the participants were divided into  control group (CON) (n = 10), the aquatic resistance training group (ART) (n = 10) and dryland resistance training group (DRT) (n = 10). The randomization method will be random numbers. Considering that, numbers 0 -10 for the control group, numbers 10 -20 for dryland resistance training and numbers  20-30 for aquatic resistance training. The researcher starts on one of the numbers and moves in the preset direction, then records the number and specifies the relevant group.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Rehabilitation with Aquatic and Dryland Resistance Training on Middle-aged Women’s PBMN Cells after Coronary Artery Bypass Grafting.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group:Intervention group 1 will do aquatic resistance training: Aquatic training will  take  place in a shallow pool (120 cm deep) at a temperature between  28-30oC. Aquatic training exercises (with 60 to 80% of one-repetition maximum for each exercise)will last for 8 weeks (3 sessions per week/ 60 minutes per session) and will be  include a warm-up (10 minutes), main activity (30-40 minutes) and cooling down (10 minutes). The main activity consist of 3 sets of upper-body dumbbell exercises including: shoulder shrugs, shoulder horizontal extension, shoulder extension with external rotation, and shoulder press with rotation, and lower body exercises with ankle weights including standing leg curls, supported squats, inner and outer thigh abduction, and sliding backward and forward with partial to full ranges of motion, with 8 repetitions during the first four weeks, and  10 repetitions during the fifth to eighth weeks. The training program of each session will differ from other sessions, and  base on the principles of kinesiology, exercise science and hydrodynamics. Intervention 2: Intervention group 2: Dryland resistance training: Dryland training program will be include eight weeks of resistance training (3 days a week / 60 minutes per session) and consist of warm-up (10 minutes), main activity (30 to 40 minutes) and cooling down (10 minutes). The  main activity will be 8 resistance sessions. It will be include machine bench press, seated cable row, inner thigh movements, Lat pull down,  Pec deck, outer thigh movements, curl-ups, hyper-extension with 2-3 sets of 12-15 repetitions with 60 % of one-repetition maximum. There are 30-second rests between exercises, and 5-minute rests between sets. One-repetition maximum test will repeat at the end of the fourth week to adjust the training protocol to the changes. Based on the results obtain through this test, the training protocol will continue until the end of the eighth week. Intervention 3: Control group: This  group will do no physical activity except everyday life affairs.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description></results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Leili Zeiaadini Dashtkhaki</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No.5, North Elahieh Ave., Nasr Blvd</address>
        <city>Kerman</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7618697677</zip>
        <telephone>+98 34 3244 5365</telephone>
        <email>lzeiaadini@yahoo.com</email>
        <affiliation>Islamic Azad University of Neyshabur</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Leili Zeiaadini Dashtkhaki</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No. 5, Elahieh Ave., Nasr  Blvd</address>
        <city>Kerman</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7618697677</zip>
        <telephone>+98 34 3244 5365</telephone>
        <email>lzeiaadini@yahoo.com</email>
        <affiliation>Islamic Azad University of Neyshabur</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Patients were included in the study if they had already had coronary bypass, had a homogeneous level of the disease, and had undergone coronary artery bypass in 3 months ago
Patients were relatively fit to  carry out the exercises</inclusion_criteria>
      <agemin>43 years</agemin>
      <agemax>56 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Patients were excluded from this study if they had unstable angina, decompensated heart failure,,
Myocardial infarction within the last month and  problematic ventricular arrhythmias
Any other limitations examined by the doctor in period of training</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Diagnosis</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group:Intervention group 1 will do aquatic resistance training: Aquatic training will  take  place in a shallow pool (120 cm deep) at a temperature between  28-30oC. Aquatic training exercises (with 60 to 80% of one-repetition maximum for each exercise)will last for 8 weeks (3 sessions per week/ 60 minutes per session) and will be  include a warm-up (10 minutes), main activity (30-40 minutes) and cooling down (10 minutes). The main activity consist of 3 sets of upper-body dumbbell exercises including: shoulder shrugs, shoulder horizontal extension, shoulder extension with external rotation, and shoulder press with rotation, and lower body exercises with ankle weights including standing leg curls, supported squats, inner and outer thigh abduction, and sliding backward and forward with partial to full ranges of motion, with 8 repetitions during the first four weeks, and  10 repetitions during the fifth to eighth weeks. The training program of each session will differ from other sessions, and  base on the principles of kinesiology, exercise science and hydrodynamics</i_keyword>
      <i_keyword>Intervention group 2: Dryland resistance training: Dryland training program will be include eight weeks of resistance training (3 days a week / 60 minutes per session) and consist of warm-up (10 minutes), main activity (30 to 40 minutes) and cooling down (10 minutes). The  main activity will be 8 resistance sessions. It will be include machine bench press, seated cable row, inner thigh movements, Lat pull down,  Pec deck, outer thigh movements, curl-ups, hyper-extension with 2-3 sets of 12-15 repetitions with 60 % of one-repetition maximum. There are 30-second rests between exercises, and 5-minute rests between sets. One-repetition maximum test will repeat at the end of the fourth week to adjust the training protocol to the changes. Based on the results obtain through this test, the training protocol will continue until the end of the eighth week.</i_keyword>
      <i_keyword>Control group: This  group will do no physical activity except everyday life affairs.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>PPAR α Gene Expression. Timepoint: At the beginning of the research and 8 weeks after doing intervention. Method of measurement: blood sample.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>ABCG8 gene expression. Timepoint: At the beginning of the research and 8 weeks after doing intervention. Method of measurement: blood sample.</sec_outcome>
      <sec_outcome>Lipid profile. Timepoint: At the beginning of the research and 8 weeks after doing intervention. Method of measurement: blood sample.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Islamic Azad University of Neyshabur</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2017-08-06</approval_date>
        <contact_name>Physical Education and Sport Science Research Center</contact_name>
        <contact_address>No.3 , 5 Miremad Ave Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
