IRCT20171119037543N2 IRCT 2018-02-03 Esfahan University of Medical Sciences Synbiotic and Antibiotic Associated Diarrhea Evaluating the Effects of Synbiotic on Preventing Antibiotic Associated Diarrhea in children admitted in Imam Hosein Hospital in Isfahan City 2017-09-23 anticipated 100 Complete https://irct.ir/trial/29150 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The type of randomization in this study is Block Randomization. In this study, Synbiotic and placebo are produced in drop forms with same shapes by pharmacology factory and get to researchers. The factory allocates an special code for each drop and researcher and patients do not have any information about the contents of drops. A table is planned and the name of patient and his/ her drop code are registered. In analyzing time, these codes and drop contents are get from factory and data are analyzed, Blinding description: In this study, researcher and patients do not have any information about contents of drops. Drops with Synbiotics and placebo are produced by pharmacology factory in same shape and special codes are allocated for each drop. The contents of drops are get from factory in analyzing time. N/A Antibiotic Associated Diarrhea. Intervention 1: Intervention group: Synbiotic powder (Protexin Restore), Starting 24 hours after starting Antibiotic therapy until 7 days after finishing Antibiotic therapy, One sachet daily, produced by Protexin Health Care Company. Intervention 2: Control group: Placebo in powder shape, Starting 24 hours after starting Antibiotic therapy until 7 days after finishing Antibiotic therapy, One sachet daily, produced by faculty of Pharmacy in Isfahan University of Medical Science. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information