IRCT20180209038673N1 IRCT 2018-04-17 Reseach depurty of Isfahan University of Medical Science ٍٍEffect of Tranexamic acid in treatment of surgical bleeding The effect of Tranexamic acid on bleeding and hemoglobin level in patients with staghorn calculus 2017-01-31 anticipated 120 Complete https://irct.ir/trial/29572 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: In this study, 120 patients with kidney stones are divided into two groups based on stone size (larger and smaller than 4 cm). Then, patients in both groups were randomly divided into two groups (drug and placebo), Randomization description: We divide each referral into two groups using a randomized table. This table is a collection of numbers. Consider numbers from 1 to 30 for intervention A and numbers 31 to 60 for control B(for both group size more and less than 4 cm). Then let's move on one of the numbers and move in one of the preset directions and assign the numbers to one of the groups. Thus, patients are completely randomly divided, Blinding description: In this study, patients did not aware about prescription drugs (placebo and medication). Also, the person who provided these drugs to patients had no information about the allocation of patients to drug or placebo. 3 staghorn calculus kidney. Intervention 1: Intervention group: Administration of 1 grTranexamic acid every 12 hours for a week(group with size more and less than 4 cm). Intervention 2: Control group: Normal Salin (group with size more and less than 4 cm). No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no reason for this decision