]>
IRCT20171231038154N1 IRCT 2018-08-17 Yazd University of Medical Sciences The effect of salbutamol administration by inhalation together with rapid and deep breathing in comparison with the standard method: A clinical trial The effect of salbutamol administration by inhalation together with rapid and deep breathing in comparison with the standard method: A clinical trial 2018-06-05 anticipated 110 Complete https://irct.ir/trial/29695 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: simple randomization, Blinding description: The participants were made aware that there were two different methods of salbutamol administration. However, they did not know to which group they belonged. Data analysis was performed using coded data and the analyzer had no knowledge of the particular group for each code. 3 DYSPNEA. Intervention 1: Intervention group: The patient is asked to breathe rapidly and deeply during medication inhalation. Three puffs are given in rapid succession with 1-second intervals. After 10-15 minutes, three more puffs are given in the same way. A peak flow meter is used to assess the patient’s response to the inhalation method at 0, 5, 10, and 15 minutes after treatment. Intervention 2: Control group: In this group, the patients are treated according to the standard method for salbutamol inhaler administration: The inhaler is placed near the patient’s mouth or between the patient’s teeth. The patient is instructed to inhale slowly simultaneous with inhaler administration, hold his/her breath for ten seconds, and then exhale. Six inhaler puffs are given, and a peak flow meter is used to assess the patients' response to the inhalation method at 0, 5, 10, and 15 minutes after treatment. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is more information is not exist
public Ebrahim Akbarzadeh
School of Medicine, Prof. Hesabi Blvd.
Yazd Iran (Islamic Republic of) 891513149 +98 35 3820 3410 dr.akbarzadeh@bums.ac.ir Yazd University of Medical Sciences scientific Ebrahim Akbarzadeh
School of Medicine, Prof. Hesabi Blvd.
Yazd Iran (Islamic Republic of) 891513149 +98 35 3820 3410 dr.akbarzadeh@bums.ac.ir Yazd University of Medical Sciences Iran (Islamic Republic of) Patients 15–75 years of age who visit the emergency department of Shahid Sadoughi Hospital in Yazd, Iran, due to bronchospasm caused by inhalation, asthma, or COPD. Lack of severe respiratory distress and absence of other underlying diseases that require treatments other than inhaled salbutamol. 15 years 75 years Both Patients who need treatments other than salbutamol, such as atrovent, combivent, or pulmicort; Patients who visit the emergency department with signs of respiratory failure, including acrocyanosis, PO2 below 60 mmHg, or PCO2 above 80 mmHg J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified Treatment - Devices Treatment - Devices Intervention group: The patient is asked to breathe rapidly and deeply during medication inhalation. Three puffs are given in rapid succession with 1-second intervals. After 10-15 minutes, three more puffs are given in the same way. A peak flow meter is used to assess the patient’s response to the inhalation method at 0, 5, 10, and 15 minutes after treatment. Control group: In this group, the patients are treated according to the standard method for salbutamol inhaler administration: The inhaler is placed near the patient’s mouth or between the patient’s teeth. The patient is instructed to inhale slowly simultaneous with inhaler administration, hold his/her breath for ten seconds, and then exhale. Six inhaler puffs are given, and a peak flow meter is used to assess the patients' response to the inhalation method at 0, 5, 10, and 15 minutes after treatment. Peak expiratory flow. Timepoint: 0, 5min, 10min, 15min. Method of measurement: peak flow meter. Yazd University of Medical Sciences Approved 2016-10-19 Research Ethics Committee of Shahid Sadoughi University of Medical Sciences Shahid Sadoughi University Campus, School of Medicine, Prof. Hesabi Blvd. Yazd Yazd Iran (Islamic Republic of)