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IRCT20141209020258N72 IRCT 2018-03-13 Arak University of Medical Sciences Comparison Different Doses Of Intrathecal Dexmedetomidine On Change Of ‎Hemodynamic Parameter And Block QualityAnd neonate’s APGAR‏ ‏‎ After Spinal ‎Anesthesia With Ropivacaine In Cesarean Section Comparison Different Doses Of Intrathecal Dexmedetomidine On Change Of ‎Hemodynamic Parameter And Block QualityAnd neonate’s APGAR‏ ‏‎ After Spinal ‎Anesthesia With Ropivacaine In Cesarean Section 2017-11-22 anticipated 120 Complete https://irct.ir/trial/29969 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization with random numbers, Blinding description: The patient is not aware of the treatment received.Participant and Analyzer are blind (double blind). 2-3 Cesarean Section. Intervention 1: Intervention group: We inject for patients 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) Intrathecal plus 2/5 micro gram dexmedetomidin in 1/5 milliliter ( total volume 4 milliliter )in first group. Intervention 2: Intervention group: We inject 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) plus 5 micro gram dexmedetomidin in 1/5 milliliter ( total volume 4 milliliter )in second group. Intervention 3: Intervention group: We inject 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) plus 7/5 micro gram dexmedetomidin in 1/5 milliliter ( total volume 4 milliliter )in third group. Intervention 4: Control group: We inject 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) plus 1/5 milliliter normal ‎salin ( total volume 4 milliliter )in forth group.‎. Yes - There is a plan to make this available What will be shared: When we publish article in journal. When: After the article is published To whom: researcher in university Conditions: If there are additional questions Where to obtain: Dr Modir How to obtain: They have to write letters to the professors and the university Comments:
public Dr Yazdi
Valiasr Hospital, Valiasr squre, Shahid Shirodi street
Arak Iran (Islamic Republic of) 3814957558 +98 86 3222 2003 yazdi@arakmu.ac.ir Arak University of Medical Sciences scientific Dr Modir
Valiasr Hospital, Valiasr squre, Shahid Shirodi street
Arak Iran (Islamic Republic of) 3814957558 +98 86 3222 2003 modir.he@gmail.com Arak University of Medical Sciences Iran (Islamic Republic of) 18-35 years ASA class I and II Patients undergoing cesarean section 18 years 35 years Female Refusal of the patient to perform spinal anesthesia Failure to perform spinal anesthesia History of taking beta-blockers and alpha-2 agonists and calcium channel blockers Cardiovascular disease Coagulation disorders Localized infection in the spinal cord Topical infection in the history of allergy to dexmedmotidine and rupivacaine arrhythmia Psychological problems Fetal distress Peripheral and central neuropathy Symptoms for the onset of labor Hypertension Preeclampsia Restriction of intrauterine growth Contraindication of spinal anesthesia Polyhydramnios Macrosomia O82 Single delivery by caesarean section Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Intervention group: We inject for patients 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) Intrathecal plus 2/5 micro gram dexmedetomidin in 1/5 milliliter ( total volume 4 milliliter )in first group. Intervention group: We inject 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) plus 5 micro gram dexmedetomidin in 1/5 milliliter ( total volume 4 milliliter )in second group. Intervention group: We inject 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) plus 7/5 micro gram dexmedetomidin in 1/5 milliliter ( total volume 4 milliliter )in third group. Control group: We inject 2/5 milliliter rupivacaine (0/5 percent(12/5 milligram) plus 1/5 milliliter normal ‎salin ( total volume 4 milliliter )in forth group.‎ Motor block. Timepoint: after start surgery. Method of measurement: bromeg scale. Sensory block. Timepoint: after start surgery. Method of measurement: bromeg scale. Pain. Timepoint: recovery and 2 hours after surgery. Method of measurement: Visual Analog Scale. Arak University of Medical Sciences Approved 2017-11-22 Ethics committee Arak University Of Medical Sciences Vice chancellor for research, Payambar azam complex, Basij squre, Sardasht, Arak Arak Markazi Iran (Islamic Republic of)