]>
IRCT20160306026938N6 IRCT 2018-10-07 Tehran University of Medical Sciences Evaluation of the effect of ajwain topical formulation in reducing chronic joint pains Evaluation of a topical formulation of Trachyspermum ammi fruit essential oil efficacy in reducing chronic arthritic pains (a 2A phase clinical study) 2018-10-07 anticipated 40 Complete https://irct.ir/trial/30444 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Osteoarthritis. Intervention 1: Ajwain essential oil (one percent) in topical formulation, will applied in pain area, two times a day alongside Diclofenac gel for one month. Intervention 2: Diclofenac gel will applied in pain area, two times a day, for one month. Yes - There is a plan to make this available What will be shared: Data would be accessible in related dissertation When: The onset of access from 2020 To whom: All the people Conditions: The documents could be accessible in case of furthur experiments Where to obtain: Iran, Tehran, Tehran University of Medical Sciences, Faculty of Pharmacy, Dr. Mahdi Vazirian How to obtain: Personal request Comments:
public Dr.Mahdi Vazirian
Pharmacognosy Lab., Second Floor, New buliding, Faculty of Pharmacy, In front of Oruji Alley, 16th Azar Ave., Enqelab Ave.
Tehran Iran (Islamic Republic of) 1417653761 +98 21 6412 1223 Vazirian_m@tums.ac.ir Tehran University of Medical Sciences scientific Mahdi Vazirian
Pharmacognosy Lab., Second Floor, New buliding, Faculty of Pharmacy, In front of Oruji Alley, 16th Azar Ave., Enqelab Ave.
tehran Iran (Islamic Republic of) 1417653761 +98 21 6412 1223 vazirian_m@tums.ac.ir Tehran University of Medical Sciences Iran (Islamic Republic of) Informed consent for taking part in the study Age between 60-80 years old Suffering from osteoarthritis pain in one or both knees Having an acceptable cognitive ability based on a short cognitive test (AMT) 60 years 80 years Both Having severe pain, Visual Analogue Scale (VAS) more than 90 History of any surgery related to this disease on the intended joint Cancer (current or any time before) and obvious symptoms of neuropsychiatric disorders Chronic use of opiates Sever chronic diseases, such as insulin-dependent diabetes Injection of analgesic within the joint in 30 days before the intervention or any programe for injection until the end of the intervention period M15.0 Primary generalized (osteo)arthritis Treatment - Drugs Treatment - Drugs Ajwain essential oil (one percent) in topical formulation, will applied in pain area, two times a day alongside Diclofenac gel for one month Diclofenac gel will applied in pain area, two times a day, for one month Pain through visual and Likert measurements. Timepoint: At the beginning of the study (before the intervention), one week and one month after commencement of topical use of Trachyspermum ammi. Method of measurement: Ontario and Master Osteoarthritis Index and KOOS (knee osteoarthritis outcome) questionnaire. Tehran University of Medical Sciences Approved 2018-02-05 Tehran University of Medical Siences Tehran University of Medical Sciences, Qods street corner, Keshavarz Blvd, Tehran, Iran. Tehran Tehran Iran (Islamic Republic of)