IRCT201305313043N8 IRCT 2013-07-10 Tehran University of Medical Sciences Cotrimoxazole as an antibiotic-lock solution in preventing Catheter–Related Bacteremia in hemodialysis patients evaluating of Cotrimoxazole as an antibiotic-lock solution in prophylaxis against Dialysis Catheter–Related Bacteremia 2013-04-04 anticipated 90 Complete https://irct.ir/trial/3053 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A CKD patients in hemodialysis. Intervention 1: In experimental group: mix 2.5 ml ampule Cotrimoxazole ( 400/80) with 0.5 ml ampule heparin5000U then 1 ml distillated water added until total volume reach to 4 ml. In the end of dialysis section, each lumen of catheter were filled by this antibiotic solution. This action will repeat during maximum 6 month for each patient. Intervention 2: In Control group:1 ml of ampule heparin 5000 U with 3 ml distillated waterwill mix until total volume of 4 ml. In the end of dialysis section, each lumen of catheter were filled by this antibiotic solution. This action will repeat during maximum 6 month for each patient.