IRCT138810223051N1 IRCT 2010-06-04 Qazvin University of Medical Sciences Comparison of the effect of intratracheal and intravenous lidocaine on bucking, cough, and emergence time at the end of anesthesia Comparison of the effect of intratracheal and intravenous lidocaine on bucking, cough, and emergence time at the end of anesthesia 2009-01-09 anticipated 60 Complete https://irct.ir/trial/3063 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Condition 1: Airways responses to emergence from general anesthesia. Condition 2: the emergence time. Intervention 1: intratracheal lidocaine 1.5 mg/kg. Intervention 2: intravenous lidocaine1.5 mg/kg.

public Marzieh-beigom Khezri

Kosar Hospital,

Qazvin Iran (Islamic Republic of) +98 28 1223 6375 mkhezri@qums.ac.irmkhezri88@gmail.com Qazvin University of Medical Sciences scientific Marzieh-beigom Khezri

Kosar Hospital

Qazvin Iran (Islamic Republic of) +98 28 1223 6376 mkhezri@qums.ac.irmkhezri88@gmail.com Qazvin University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion criteria: aged 18 to 60 years, scheduled for elective minor orthopedic surgery, lower abdominal surgery or gynecologic surgery Exclusion criteria: history of laryngeal or tracheal surgery or pathology, bronchial asthma, addiction and smoking., coexisting systemic illness increased intracranial pressure, severe cardiac disease, active upper respiratory tract infections, increased risk for perioperative aspiration of gastric contents, combined epidural/general anesthetic techniques, consumption of cardiovascular medications such as ACE Inhibitors 18 years 60 years Both Y55.7 Y48.4 Anaesthetic, unspecified Anaesthetic, unspecified Prevention Prevention intratracheal lidocaine 1.5 mg/kg intravenous lidocaine1.5 mg/kg The number of bucking and coughs. Timepoint: before tracheal extubation and thirty minutes after extubation. Method of measurement: bucking and coughing were evaluated on a 3-point scale. The emergence time. Timepoint: the time from discontinuation of drugs to extubation of patients at awake condision. Method of measurement: In minutes. Heart rate (HR). Timepoint: immediately after tracheal extubation. Method of measurement: with noninvasive monitoring. Systolic blood pressure. Timepoint: immediately after tracheal extubation. Method of measurement: with noninvasive monitoring. Diastolic blood pressure. Timepoint: immediately after tracheal extubation. Method of measurement: with noninvasive monitoring. Qazvin University of Medical Sciences Approved 2008-12-29 Qazvin University of Medical Sciences Shahid Bahonar Blvd. Qazvin Iran (Islamic Republic of)