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IRCT20161204031227N1 IRCT 2021-08-09 University of social welfare and rehabilitation sciences The efficacy of cognitive training intervention on cognitive functions of the older adults with mild cognitive impairment The effects of attention and working memory-based cognitive intervention on behavioral and neurological evidences of cognitive functions in older adults with mild cognitive impairment 2017-09-05 anticipated 30 Complete https://irct.ir/trial/30675 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other, Randomization description: In this study, the patients were allocated to the intervention and control groups using balanced blocked randomization method. 4 blocks of size 8 with equal proportion of patients assigned to each group (intervention group A, and control group B) were used (i.e., 16 patients in each group). Assignment of individuals to these two groups was done by the laboratory secretary who was unaware of the selected codes. N/A Mild cognitive impairment. Intervention 1: Intervention group: In the Intervention group, After the evaluation session (using cognitive function evaluation tests) and recording of Event-Related Potentials (ERPs) participants were trained using Attentive Rehabilitation of Attention and Memory app (ARAM) in 10 sessions of 45 minutes twice a week and then re-evaluated in the twelfth session. The ARAM is a computerized cognitive rehabilitation program with different tasks for training attention and working memory. The program consisted of 10 graded progressive tasks. All tasks had 10 levels and participants could shift to the higher level after gaining 80 percent of score in each level. Intervention 2: Control group: Participants assigned to the control group did not receive any intervention and were on the waiting list and could receive cognitive intervention after a 3-month follow-up period. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Mahdieh Esmaeili Tarzi
Koodakyar Ave., Danshjou Blvd., Velenjak
Tehran Iran (Islamic Republic of) 1985713871 +98 21 8876 1695 mah.esmaeili@uswr.ac.ir University of social welfare and rehabilitation sciences scientific Mahdieh Esmaeili Tarzi
Koodakyar ave., Daneshjou Blvd., Velenjak
Tehran Iran (Islamic Republic of) ۱۹۸۵۷۱۳۸۷۱ +98 21 8876 1695 mah.esmaeili@uswr.ac.ir University of social welfare and rehabilitation sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Monolingual Persian-speaking elderly people over 60 years old with education higher than elementary level Memory complaint by the patient or a close relative Objective Memory impairment in Rey Auditory Verbal Learning Test (1.5 SDs below the age-matched and education-matched norms) Independence in activities of daily living and complex activities of life Normal global cognitive function (Mini-Mental Status Examination score > 22 ) No evidence of dementia No depression (Geriatric Depression Scale score < 5) 60 years 100 years Both History of a variety of neurological, medical and psychiatric disease including a history of stroke in the last 12 months, cardiovascular disease, schizophrenia, personality disorder, and bipolar disorder History of substance abuse Unmodified sensory impairment and hand mobility impairment History of participating in cognitive intervention programs in the last 6 months G31.84 Mild cognitive impairment, so stated Rehabilitation N/A Intervention group: In the Intervention group, After the evaluation session (using cognitive function evaluation tests) and recording of Event-Related Potentials (ERPs) participants were trained using Attentive Rehabilitation of Attention and Memory app (ARAM) in 10 sessions of 45 minutes twice a week and then re-evaluated in the twelfth session. The ARAM is a computerized cognitive rehabilitation program with different tasks for training attention and working memory. The program consisted of 10 graded progressive tasks. All tasks had 10 levels and participants could shift to the higher level after gaining 80 percent of score in each level. Control group: Participants assigned to the control group did not receive any intervention and were on the waiting list and could receive cognitive intervention after a 3-month follow-up period Selective attention. Timepoint: Before intervention, immediately after 12 sessions of intervention and 3 months later. Method of measurement: Attention Network Test (ANT). Working memory. Timepoint: Before intervention, immediately after 12 sessions of intervention and 3 months later. Method of measurement: N-back test. Amplitude of N100 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test. Latency of N100 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test. Amplitude of P300 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test. Latency of P300 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test. Episodic memory score. Timepoint: Before intervention, Immediately after 12 sessions of intervention and 3 months later. Method of measurement: Rey Auditory Verbal Learning Test (RAVLT). University of social welfare and rehabilitation sciences Approved 2016-10-09 Ethics committee of University of Social Welfare and Rehabilitation Sciences Koodakyar Ave, Daneshjou Blvd, Velenjak Tehran Tehran Iran (Islamic Republic of)