IRCT20171113037424N2 IRCT 2019-03-05 Shahed University Effect of Nigella Sativa in Hypothyroidism The Efficacy of Oral Consumption of Nigella Sativa with Placebo on Serum TSH in Patients with Hypothyroidism treated with Levothyroxine 2018-03-21 anticipated 42 Complete https://irct.ir/trial/30770 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization of control and intervention groups. Participants will be divided into the control and intervention group using a simple randomization model (computer randomization method) and also according to the random number table, Blinding description: 42 patients with hypothyroidism and undergoing treatment will be selected based on inclusion criteria. According to the computer based randomization table, medications (placebo and nigella sativa) will be given by patients with a specific Cod. Patients, researcher and analyzers are unaware of the type of medication. 3 Hypothyroidism. Intervention 1: Intervention group: 2g/day of Nigella sativa powder equivalent to four capsules 250 mg and twice a day for 2 months plus levothyroxine tablets. Intervention 2: Control group: ،placebo group (four 250 mg capsules containing starch powder and twice a day) for 2 months with levothyroxine drug. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information