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IRCT20180503039511N1 IRCT 2018-06-21 Esfahan University of Medical Sciences The effect of Curcumin on Polycystic Ovary Syndrome. Evaluation of the Effect of Curcumin supplementation on Mood Disorders, Lipid, Glycemic and Oxidative Stress Indexes, High-Sensitivity C-reactive Protein, in Women with Polycystic Ovary Syndrome(PCOS). 2018-04-21 anticipated 60 Complete https://irct.ir/trial/31036 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Use the randomized block model (random number table) and place each referral in the intervention or control group, Blinding description: In this study, the patients and the physician and the people who will perform the tests will not be aware of the fact that the person is using Curcumin supplement or placebo, and only the investigator and data analyst will know how to blind. 3 Polycystic Ovary Syndrome. Intervention 1: Intervention group: For 30 patients with Polycystic Ovarian Syndrome, selected by a specialist based on the Rotterdam index, a written consent is given after explaining the topic of the study. In this double-blind clinical trial, 500 mg Curcumin supplement, Karen Yazd, a pure extract of 95% turmeric, are recommended to take two capsules daily (1 g / day) with food.The duration of the intervention is 6 weeks and patients are taken from the patients at the beginning and the end of the intervention by fasting blood samples.Meanwhile, people respond to fill in short international physical activity questionnaires and depression, anxiety and stress personally, as well as the form of food intake, and after explaining how to write their diet, we ask them to bring them in next time. Intervention 2: Control group: Control group: For 30 patients with Polycystic Ovarian Syndrome, selected by a specialist based on the Rotterdam index, a written consent is given after explaining the topic of the study. In this double-blind clinical trial, Placebo (starch) in the same shape and packaging, Iran, Karen Yazd, recommends daily consumption of two capsules (1 g / day) with food.The duration of the intervention is 6 weeks and patients are taken from the patients at the beginning and the end of the intervention by fasting blood samples.Meanwhile, people respond to fill in short international physical activity questionnaires and depression, anxiety and stress personally, as well as the form of food intake, and after explaining how to write their diet, we ask them to bring them in next time. Yes - There is a plan to make this available What will be shared: Information about Depression Anxiety Stress Scale Questionnaire. When: 6 months after printing results To whom: Researchers of Scientific references. Conditions: Data will only be used in the area of their subject matter. Where to obtain: s.sohaei@nutr.ac.ir 09058798237 983136681378+ Sara Sohaei Isfahan, Azadi Square, School of Nutrition How to obtain: They will send the message to the email after 10 days. Comments:
public Sara Sohaei
Azadi Square, School of Nutrition
Isfahan Iran (Islamic Republic of) 81746-73461 +98 31 3773 5516 s.sohaei@nutr.mui.ac.ir Esfahan University of Medical Sciences scientific Sara Sohaei
Azadi Square, School of Nutrition
Isfahan Iran (Islamic Republic of) 81746-73461 +98 31 3773 5516 s.sohaei@nutr.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) PCOS diagnosis by a Specialist (Base on Rotterdam benchmark) Women aged 18 to 40 Years Old (It is preferable not to be at the Age of Development or Menopause). Body mass index larger equal to 25, smaller and equal to 35. stability in the type and dose of medication in the last 6 months. Lack of acute heart disease, Increased Prolactin levels, Liver, Kidney, Digestive, Thyroid and Diabetes, Androgens secreting Tumors. Use of antioxidant supplements and drugs that affect inflammatory and oxidative stress factors. Drug in the last 6 months 18 years 40 years Female Unwilling to participate in the study Pregnancy Misdiagnosis of demographic or anthropometric information E28.2 Polycystic ovarian syndrome Treatment - Drugs Treatment - Drugs Intervention group: For 30 patients with Polycystic Ovarian Syndrome, selected by a specialist based on the Rotterdam index, a written consent is given after explaining the topic of the study. In this double-blind clinical trial, 500 mg Curcumin supplement, Karen Yazd, a pure extract of 95% turmeric, are recommended to take two capsules daily (1 g / day) with food.The duration of the intervention is 6 weeks and patients are taken from the patients at the beginning and the end of the intervention by fasting blood samples.Meanwhile, people respond to fill in short international physical activity questionnaires and depression, anxiety and stress personally, as well as the form of food intake, and after explaining how to write their diet, we ask them to bring them in next time. Control group: Control group: For 30 patients with Polycystic Ovarian Syndrome, selected by a specialist based on the Rotterdam index, a written consent is given after explaining the topic of the study. In this double-blind clinical trial, Placebo (starch) in the same shape and packaging, Iran, Karen Yazd, recommends daily consumption of two capsules (1 g / day) with food.The duration of the intervention is 6 weeks and patients are taken from the patients at the beginning and the end of the intervention by fasting blood samples.Meanwhile, people respond to fill in short international physical activity questionnaires and depression, anxiety and stress personally, as well as the form of food intake, and after explaining how to write their diet, we ask them to bring them in next time Malondialdehyde. Timepoint: The beginning and the end of the study. Method of measurement: Biochemistry. Total Antioxidant Capacity. Timepoint: The beginning and the end of the study. Method of measurement: Biochemistry. Mean changes in the level of the C reactive protein. Timepoint: The beginning and the end of the study. Method of measurement: Biochemistry. Depression anxiety stress score. Timepoint: The beginning and the end of the study. Method of measurement: Stress Anxiety Depression Questionnaire 7 question. Esfahan University of Medical Sciences Approved 2018-02-09 Isfahan University of Medical Sciences Faculty of Nutrition and Food Sciences., Hezar-Jerib St., Azad Square. Isfahan Isfehan Iran (Islamic Republic of)