IRCT20170923036334N2 IRCT 2018-09-02 Islamic Azad University The effect rhFSH drug in infertile men The effect rhFSH drug on sperm parameters,choromatin status and clinical outcomes of infertile men candidates for ICSI 2018-02-16 anticipated 50 Complete https://irct.ir/trial/31233 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, simple individual randomization by use of randlist software is applied, Blinding description: In this study, participants were not aware of the drug dose and efficacy in knowing the use of the drug, which is why they are blind. 1-2 oligospermia. Intervention 1: 1-Control group:In the control group, at least 25 ICSI patients were not treated with rhFSH and sperm analysis was performed based on WHO-2010 criteria and DNA damage and blood serum was taken to measure hormones (T, LH, FSH) ) be done. Intervention 2: 2-Intervention group: At least 25 patients with oligo-spermatozoa who were treated with rhFSH (gel) for a period of 2 or 3 months (twice a week for subcutaneous injection), and serum samples were taken to measure hormones (T, LH, FSH). And the semen is prepared after taking the medication (between 48 and 72 hours from the closest approach) into sterile containers for various tests (sperm analysis, based on WHO-2010 benchmark criteria and DNA damage). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to the confidentiality of the data, no decision is taken to publish it and no further information is available