IRCT20180525039828N1 IRCT 2018-08-15 Kashan University of Medical Sciences Effect of vitamin D supplementation in treatment of diabetic hemodialysis patients The effects of vitamin D supplementation compared with the placebo on gene expression related to insulin and lipid in diabetic hemodialysis patients 2018-01-14 anticipated 60 Complete https://irct.ir/trial/31538 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: To decrease potential confounding effects, all participants will have stratified randomization according to BMI (<25 and ≥25 kg/m2) and age (<50 and ≥50 y). Then, participants in each block will be randomly allocated into two treatment groups to take either vitamin D supplements or placebo. Randomization will be done by the use of computer softwares, Blinding description: Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at the Akhavan clinic, who is not involved in the trial and not aware of random sequences, will be assigned the participants to the numbered bottles of capsules. 3 Hemodialysis. Intervention 1: Intervention group: 50000 IU vitamin D every 2 weeks (Zahravi, Tabriz, Iran), for 12 weeks orally. Intervention 2: Control group: Placebo (Barij Essence, Kashan, Iran) every 2 weeks, for 12 weeks orally. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available