IRCT20180303038927N1 IRCT 2019-01-01 Qazvin University of Medical Sciences The effect of adding buspirone to SSRIs in the treatment of obsessive-compulsive disorder Comparison of the effectiveness of adding Buspirone to SSRI in the control of signs and symptoms of Obsessive-Compulsive Disorder 2019-01-21 anticipated 60 Complete https://irct.ir/trial/31879 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Restricted randomization with Random Allocation Rule, Blinding description: this study is a Single Blind Study, that Interventional and Control group are not aware of their group.but the responsibe person is aware and know them. 3 Obsessive Compulsive Disorder. Intervention 1: Intervention group: 30 patients to recieve Sertraline plus Buspirone for 3 months 50 to 200 mg Sertraline plus until 30 mg Buspirone. Intervention 2: In 30 Placebo group that only recieve sertraline 50-200 mg plus placebo that is exactly like the tablet of Buspirone and contains cellulose or starch. Yes - There is a plan to make this available What will be shared: The Augmentation effect of Buspirone to Sertraline IN OCD treatment When: about one year To whom: for academic persons and patients Conditions: for persons wants to know about OCD Where to obtain: articles How to obtain: by searching on the Internet Comments: OCD patients suffer from their illness,they have no complete cure with one drug,augmentation may be more efficient