]>
IRCT20140612018077N2 IRCT 2018-10-24 Iran University of Medical Sciences The effect of physical activity on people with Parkinson disease The effect of physical activity on cognition, vision and motor function in people with Parkinson disease and its animal model 2018-11-11 anticipated 90 Complete https://irct.ir/trial/31977 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: First, people with Parkinson's disease will be selected as available, and then randomly assigned into two groups randomly without any blocks, Blinding description: This study will be triple-blind study. In this study, patients, therapist and data analyst will not be aware of the type of groups. N/A Parkinson's Disease. Intervention 1: Parkinson's disease (PD) is one of the most common progressive neurodegenerative disorders. Physical exercise takes into account an important protective approach to prevent abnormal function and cell death in the brain. Beneficial effects including molecular changes in the brain to increase memory and learning might reduce apoptosis in Retinal cells. Therefore, it is important to seek more effective therapeutic interventions as well as low-cost ones for PD. In this study, the mechanism of its effect in PD and its animal model will be considered. Intervention 2: Control group: In this study, the control group will not receive any specific training. Yes - There is a plan to make this available What will be shared: IPD collected for the primary outcome measure only When: starting 6 months after publication To whom: only available for people working in academic institutions Conditions: NO Where to obtain: email addresses How to obtain: NO Comments:
public Maryam Mehdizadeh
Iran University of Medical Sciences, Shahid Hemmat Highway, Tehran,1449614535,IRAN.
Tehran Iran (Islamic Republic of) 14665-354 +98 21 8843 3583 maryam.mehdizadeh_22@yahoo.com Iran University of Medical Sciences scientific Maryam Mehdizadeh
Iran University of Medical Sciences, Shahid Hemmat Highway, Tehran,1449614535,IRAN.
Tehran Iran (Islamic Republic of) 14665-354 +98 21 8843 3583 maryam.mehdizadeh_22@yahoo.com Iran University of Medical Sciences Iran (Islamic Republic of) People diagnosed with Parkinson's Disease Ability to walk independently for a distance of at least 10 meters with and without asistive devices Ability to perform the hardest level of laboratory tests Have a Mini Mental State Examination score equal or more than 21 30 years 80 years Both Having another disease before entering the study G20 Parkinson's disease Rehabilitation Rehabilitation Parkinson's disease (PD) is one of the most common progressive neurodegenerative disorders. Physical exercise takes into account an important protective approach to prevent abnormal function and cell death in the brain. Beneficial effects including molecular changes in the brain to increase memory and learning might reduce apoptosis in Retinal cells. Therefore, it is important to seek more effective therapeutic interventions as well as low-cost ones for PD. In this study, the mechanism of its effect in PD and its animal model will be considered. Control group: In this study, the control group will not receive any specific training. Postural control (Balance improvement after treatment). Timepoint: Before and after intervention. Method of measurement: force plate in bio-mechanic lab. Cognitive function based on changes in BDNF protein. Timepoint: Before and After intervention. Method of measurement: Study of serum BDNF levels by analyzing blood samples. Iran University of Medical Sciences Approved 2018-09-25 Ethics committee of Iran University of Medical Sciences ran University of Medical Sciences, Shahid Hemmat Highway, Tehran,1449614535,IRAN. Tehran Tehran Iran (Islamic Republic of)