]>
IRCT20180615040104N1 IRCT 2018-10-01 Ardabil University of Medical Sciences The effect of intravenous ibuprofen and tramadol on shivering after abdominal surgery with general anesthesia Comparisons between effect of intera venous Ibuprofen with Tramadol for prevention of postoperative shivering with general anesthesia 2018-02-13 anticipated 90 Complete https://irct.ir/trial/32105 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients are randomly divided into three groups. Initially, 120 envelopes will be prepared that 40 with letters (A) and 40 with letters (B) and 40 envelopes with letters (E) written. The drugs will be encoding, so that the injector And the checklist registrar is not aware of the quiddity of the codes. The drugs are drawn in two Session (in volume of 2 cc) and in the same color of the syringes and the code is recorded on them. The technician outside of the research group prepares drugs and the researcher does not know the quiddity of the codes, type of injectable drugs and drugs are injected according to the selected code. Then an envelope is randomly selected and the drug that containing the code in the envelope is injected to the patient and the results are recorded in the checklist, Blinding description: At first three boxes with codes A, B and C were prepared. Then the medications were given to an anesthetic technician. He was asked to place the vials of each drug in one of the boxes. Vials should be similar and without names. The packets are packed in each group and then the researcher randomly selects one of the envelopes and injects and records the results in checklists. N/A Cholelithiasis, cholecystitis and other diseases associated with gallbladder. Intervention 1: Interventions group1: Tramadol ampoule 1 mg / kg. Intervention 2: Interventions group2: intravenous ibuprofen ampoule 800 mg. Intervention 3: Control group: Placebo (normal saline with the same volume and shape with the intervention groups). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.
public Ghodrat Akhavan Akbari
Medical Univaersity. university Ave.
Ardabil Iran (Islamic Republic of) 53141-56198 +98 45 3351 2006 g.akbari@arums.ac.ir Ardabil University of Medical Sciences scientific Ghodrat Akhavan Akbari
Medical University. University Ave.
Ardebil Iran (Islamic Republic of) 53141-56198 +98 45 3351 2006 g.akbari@arums.ac.ir Ardabil University of Medical Sciences Iran (Islamic Republic of) Patients undergoing cholecystectomy (surgical) Male patients referred to Ardabil Fatemi Hospital in the range of 20 to 70 year. Female patients referred to Ardabil Fatemi Hospital in the range of 20 to 70 year. 20 years 70 years Both Severe cardiovascular disease Liver and kidney disorders Peptic ulcer disease Muscular disease Patients with history of the blood transfusions or blood products during surgery Patients with history of seizure Surgeries with a duration of more than 2 hours k808,182 Calculus of gallbladder with acute cholecystitis, Calculus of gallbladder with other cholecystitis, Calculus of gallbladder without cholecystitis Prevention Prevention Placebo Interventions group1: Tramadol ampoule 1 mg / kg Interventions group2: intravenous ibuprofen ampoule 800 mg Control group: Placebo (normal saline with the same volume and shape with the intervention groups) Check in scale of shivering. Timepoint: check in scale of post operative shivering based on observation muscle movement in recovery and scored. Method of measurement: score. Check in scale of post operative nausea and vomiting and sedation and pain. Timepoint: check in scale of post operative indication of nausea and vomiting and sedation and pain based on APFEL & RAMSAY score and VAS. Method of measurement: score. Ardabil University of Medical Sciences Approved 2018-02-17 Medical University of Ardebil No. 90, Mlek Ashtar Alley, Otobosrani St., Ardebil City Ardebil Ardabil Iran (Islamic Republic of)