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IRCT20180521039761N1 IRCT 2018-08-25 Boushehr University of Medical Sciences Evaluation of the effect of SRP on levels of salivary biomarkers of mmp7 and mucin4 in patients with moderate to severe chronic Tissue Inflammation Evaluation of the effect of non-invasive periodontal therapy(SRP) on levels of salivary biomarkers of mmp7 and mucin4 in patients with moderate to severe chronic periodontitis 2018-05-22 anticipated 40 Complete https://irct.ir/trial/32319 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Diagnostic, Randomization description: The study samples were selected based on the criteria for entering and leaving the study. For random allocation random sampling, two groups of intervention and control group were used. N/A Moderate to severe chronic periodontitis. Intervention 1: Intervention group: A group of patients for whom oral contraceptive practice (OHI) and oral administration of 2 ml of 10 ml of .2% chlorhexidine d-gluconate solution are administered for one week for oral administration. Intervention 2: Control group: For the control group, only Oral Hygiene (OHI) and oral chloride.2% are prescribed. Patients are asked to refer to the saliva for one month after receiving saliva. Yes - There is a plan to make this available What will be shared: 0 When: 0 To whom: 0 Conditions: 0 Where to obtain: 0 How to obtain: 0 Comments: 0
public Najmeh Shooraki
Heidary ave.
Bushehr Iran (Islamic Republic of) 7514633341 +98 77 3332 2081 N.shooraki@bpums.ac.ir Boushehr University of Medical Sciences scientific Najmeh Shooraki
Mosalla Ave., moallem Blvd., kuy-e-bandar
Bushehr Iran (Islamic Republic of) 7514633341 +98 77 3332 3226 n.shooraki@bpums.ac.ir Boushehr University of Medical Sciences Iran (Islamic Republic of) Patients with moderate to severe periodontitis from 30 to 60 years of age 30 years 60 years Both Pregnancy History of smoking and alcohol Chronic inflammatory diseases of the skin and oral mucosa Systemic diseases that affect periodontal conditions Periodontal acute diseases such as periodontal abscesses Radiographic evidence of visible bone resorption in posterior B.W K05.3 Chronic periodontitis Diagnosis Diagnosis Intervention group: A group of patients for whom oral contraceptive practice (OHI) and oral administration of 2 ml of 10 ml of .2% chlorhexidine d-gluconate solution are administered for one week for oral administration. Control group: For the control group, only Oral Hygiene (OHI) and oral chloride.2% are prescribed. Patients are asked to refer to the saliva for one month after receiving saliva MUCIN4/MMP7. Timepoint: Before starting the study and one month later. Method of measurement: ELISA Kit. Bushehr university of medical sciences Approved 2018-03-12 Ethics committee of bushehr university of medical sciences Dental clinic; Heidari ave. bushehr Boushehr Iran (Islamic Republic of)