]>
IRCT20090526001952N10 IRCT 2019-04-23 Tehran University of Medical Sciences Effect of Aspirin On treatment of endometriosis Comparison of the effect of aspirin and placebo on pelvic pain and the number and size of endometriosis lesions after surgery 2019-01-05 anticipated 122 Complete https://irct.ir/trial/32422 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Our sample size is 122 people, with 61 people in each group. Block randomization method was designed by epidemiologist using STATA version 13 software. The number of participants in each block is 4, Blinding description: At the present study, we will use a placebo that is completely similar to aspirin, so that the physician and the patient will not be aware of the type of the intervention. Also, the person evaluating the outcomes is a third person who is unaware of the random allocation process and type of treatment. A statistician who is unaware of the type of interventions in each group will analyse the data. So, participants, the person evaluating the outcome, the physician and the analyzer, are all blind. 3 Endometriosis. Intervention 1: Intervention group: OCP and Asprin 80 mg daily for 6 months. Intervention 2: Control group: Intervention group: OCP and placebo daily for 6 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The research team has not yet made a decision on how to publish the results or the statistical analysis map.
public Ashraf Moini
Eastern 162th St, Baghdarnia st, Resalat Highway, Tehranpars, Tehran ,Iran
Tehran Iran (Islamic Republic of) 1653915981 +98 21 7771 9922 A_moini@royaninstitute.org Tehran University of Medical Sciences scientific Ashraf Moini
Eastern 162th St, Baghdarnia st, Resalat Highway, Tehranpars, Tehran ,Iran
Tehran Iran (Islamic Republic of) 1653919581 +98 21 7771 9922 A_moini@royaninstitute.org Tehran University of Medical Sciences Iran (Islamic Republic of) Patients with endometriosis undergoing surgery 18-40 years old 18 years 40 years Female All people who have contraindications to taking OCPs and aspirin (platelet disorders, bleeding disorders, gastrointestinal bleeding, severe dehydration, liver failure) Malignancy Willing to become pregnant pregnancy N80 Endometriosis Treatment - Drugs Placebo Intervention group: OCP and Asprin 80 mg daily for 6 months Control group: Intervention group: OCP and placebo daily for 6 months Pelvic pain. Timepoint: Before,3 and 6 months after the surgery. Method of measurement: Visual analog scale. Dysmenorrhea. Timepoint: Before,3 and 6 months after the surgery. Method of measurement: Visual analog scale and Questionnaire. Dyspareunia. Timepoint: Before,3 and 6 months after the surgery. Method of measurement: Questionnaire. Menstrual bleeding. Timepoint: Before , 3 and 6 months after surgery. Method of measurement: Questionnaire. The size and the number of masses. Timepoint: Before , 3 and 6 months after surgery. Method of measurement: Sonography. Tehran University of Medical Sciences Approved 2018-07-25 Ethics committee of Tehran University of Medical Science Qods Street, Keshavarz Bulevard Tehran Tehran Iran (Islamic Republic of)