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IRCT20180705040351N1 IRCT 2018-07-17 Islamic Azad University The effect Allicin and Silybum Marianum supplementation on some of the antioxidant and oxidative indicators SOD,MDA,TAC Comparison of the effect a period of consumption Allicin and Silybum Marianum supplementation with four weeks wrestling selective training on some of the antioxidant and oxidative indicators in trained wrestlers 2018-07-23 anticipated 33 Complete https://irct.ir/trial/32474 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: First, it is purposeful and selective and then randomly, Blinding description: Prior to the commencement of the study, supplementary canisters and placebo can be marked by a person other than the researcher so that the knowledge of the researcher and the learners about the type of capsules received is not taken into consideration. The supplement and placebo will be administered under the supervision of the same person (he is a doctor). Which also monitors the subjects. 4 antioxidant and oxidative indicators. Intervention 1: Intervention group: first, 24 hours after blood sampling, the subjects received 3 tablets 300 mg containing 1/1 gram of allicin for one month each day made in Isfahan Pharmaceutical Company. Pills will be put in powder form in the capsule. Intervention 2: Intervention group: second, 24 hours after blood sampling, the subjects received 3 tablets containing 140 mg of silybium maryanum for one month each day made in Isfahan Pharmaceutical Company. Pills will be put in powder form in the capsule. Intervention 3: Control group:Third, 24 hours after blood sampling, the subjects received 3 tablets containing Starch. Pills will be put in powder form in the capsule. Yes - There is a plan to make this available What will be shared: By giving the resources to all people is allowed. When: Next 3 months To whom: By giving the resources to all people is allowed. Conditions: By giving the resources to all people is allowed. Where to obtain: Email researcher How to obtain: Send an email to the researcher Comments:
public Mohammad Hassani
Qom- Pardisan - Islamic Azad University of Qom
Qom Iran (Islamic Republic of) ۳۷۴۹۱۱۳۱۹۱ +98 25 3665 2981 msv.55.hasani@gmail.com Islamic Azad University scientific Mohammad Hassani
Qom- Pardisan - Islamic Azad University of Qom
Qom Iran (Islamic Republic of) ۳۷۴۹۱۱۳۱۹۱ +98 25 3665 2981 msv.55.hasani@gmail.com Islamic Azad University Iran (Islamic Republic of) Wrestlers who have had a continuous training record of at least five years. At least one championship title has been gained at the provincial level. 15 years 20 years Male Prevention Prevention Placebo Intervention group: first, 24 hours after blood sampling, the subjects received 3 tablets 300 mg containing 1/1 gram of allicin for one month each day made in Isfahan Pharmaceutical Company. Pills will be put in powder form in the capsule. Intervention group: second, 24 hours after blood sampling, the subjects received 3 tablets containing 140 mg of silybium maryanum for one month each day made in Isfahan Pharmaceutical Company. Pills will be put in powder form in the capsule. Control group:Third, 24 hours after blood sampling, the subjects received 3 tablets containing Starch. Pills will be put in powder form in the capsule. Compare differences in the values of SOD change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company. Compare differences in the values of MDA change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, Water bath made in Iran, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company. Compare differences in the values of TAC change in different groups. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Spectrophotometer made in USA, centrifuge(hermel z310- germany), The kits and chemicals required will also be supplied by Iran's Navand Salamat Company. Score Muscle soreness. Timepoint: At the beginning of the study (before the intervention) and one month after taking supplements and exercise ( one hour after training, 24 hours (fasting) and 36 (fasting). Method of measurement: Borg Pain Questionnaire. Islamic Azad University Approved 2018-06-08 Institutional Research Ethics Committee Islamic Azad University Boroujerd-Branch Navab Square, Imam Khomeini Complex (Imam Khomeini), Borujerd Town Arak Markazi Iran (Islamic Republic of)