IRCT20150713023190N4 IRCT 2018-08-05 Rafsanjan University of Medical Sciences effect of Melissa officinalis on the anxiety Investigating the effect of Melissa officinalis extract on the anxiety of patients undergoing orthopedic surgeries 2018-08-06 anticipated 80 Complete https://irct.ir/trial/32830 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Random stratifying using minimization, Blinding description: In order to blind patients, the pharmacist is asked to identify the drug and the placebo with numbers one and two so that the researcher does not know about the content of the capsules (drug or placebo). Patients are also given the capsules numbered 1 and 2 and the patient also doesn't know about the content of the capsules. The blinding will also be available for the analyzer, and after completing the analysis, the pharmacist will be asked to disclose the content of the capsules. 3 Surgery anxiety. Intervention 1: Intervention group: Patients in the intervention group receive 500 mg capsules containing Melissa officinalis extract at 4 and 10 pm before the surgery. Intervention 2: Control group: his group receives a 500 mg capsule containing starch as a placebo. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Confidentiality of data