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IRCT20180804040695N1 IRCT 2018-10-27 Zanjan University of Medical Sciences Study of the effect of Nandrolone ampoule in facilitating the separation of mechanical ventilation effectiveness study of nandrolone on facilitate weaning in prolonged weaning patients 2018-10-23 anticipated 30 Complete https://irct.ir/trial/33148 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization, Blinding description: The researcher and assistant researcher do not know which medicine was injected. 3 All patients have long-term ventilation with the same Apache screw. Intervention 1: Intervention group: تزریق دارو نماNandrolone intramuscular injection twice a day for one week. Intervention 2: Control group: Injection drug. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no similar article and a new study
public Mohammad Reza Zeraati
No. 4513956183, Mousavi Hospital, Gavazang Ave., Zanjan, Iran
Zanjan Iran (Islamic Republic of) 4513956183 +98 24 3313 0000 mohammadrezazeraati@zums.ac.ir Zanjan University of Medical Sciences scientific Mohammad Reza Zeraati
No. 4513956183, Mousavi Hospital, Gavazang Ave., Zanjan, Iran
Zanjan Iran (Islamic Republic of) 4513956183 +98 24 3313 0000 mohammadrezazeraati@zums.ac.ir Zanjan University of Medical Sciences Iran (Islamic Republic of) Patient with long-term separation of mechanical ventilation (over SBT 3 or 7 days from the first SBT to 3 weeks) separate inspiration weakness (caused by myopathy or neuropathy caused by respiratory muscles for any reason). Age 20 to 70 years Sepsis or febrile illness that causes a kind of neuropathy. Lack of lung disease (such as nano-pulmonary pleural effusion-respiratory failure-pulmonary mass and COPD) Patients with the same nutrition or gavage Length of stay in ICU less than 21 days. No electrolyte imbalance NIF having> 30- 20 years 70 years Both Reintubation Patient death before ICU clearance NPO becoming patient during examination Incidence of pulmonary edema, ARDS, pleural effusion and ventilator pneumonia Electrolyte disturbances (hypokalemia, etc.) at any time during the study. Dissatisfaction with the patient's companions Contraindication for the injection of nandrolone such as CHF, recent history of IHD or MI, obstructive europoplasty (BPH) in men, hematocrit over 50 (erythrocytosis), and chronic kidney and liver disease (Increase LFT) Placebo Placebo Intervention group: تزریق دارو نماNandrolone intramuscular injection twice a day for one week Control group: Injection drug Facilitate separation of ventilators in patients with long-term mechanical ventilation. Timepoint: In 3 stages, 3, 5 and 7 per week, variables such as static capacity, R.S.R.I, I.W.I, CORP Index. Method of measurement: Questionnaire (Static Compliace, R.S.R.I, I.W.I, CORP Index). Zanjan University of Medical Sciences Approved 2018-04-29 Ethics committee of Zanjan University of Medical Sciences Zanjan University of Medical Sciences , Azadi Square Zanjan Zanjan Iran (Islamic Republic of)