IRCT20180809040747N1 IRCT 2018-09-02 Tehran University of Medical Sciences The effect of naltrexone in lichen planopilaris Comparison of efficacy and safety of low-dose naltrexone with placebo in lichen planopilaris: A randomized double-blinded clinical trial 2018-04-04 anticipated 34 Complete https://irct.ir/trial/33214 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be assigned to any of two groups by 4-spot permuted blocks with 1:1 ratio, Blinding description: Participants are blinded by using identical placebos (in shape, package, and flavor). The principal investigator who assesses efficacy and individuals who assess safety are also blinded to assignment. The analyzer is blinded. 2 Lichen Planopilaris. Intervention 1: Intervention group: Oral tab naltrexone 3mg once a day at 1 hr before sleep plus topical Clobetasol ointment once at night for 6 months. Intervention 2: Control group: Oral Tab Placebo once a day at 1 hr before sleep plus topical clobetasole ointment once a day at night for 6 months. Yes - There is a plan to make this available What will be shared: Patient dataset, all collected data will be shared. When: After the final report, the data will be available forever. To whom: For academic individuals and also for whom serve in the pharmaceutical business. Conditions: The only criterion will be citing the name of principal investigators in resultant academic works. Where to obtain: By contacting principal investigators via this email: f.salarvand89@gmail.com How to obtain: Sending the email by the requester including their academic position or business information Comments: