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IRCT20140519017756N45 IRCT 2018-08-29 Birjand University of Medical Sciences Impact of adding bronchoscopic suction to the routine therapy of pneumonia Comparison of the effect of the routine procedure and the routine procedure supplemented by bronchoscopic suctioning in treating ventilator-associated pneumonia in patients admitted to the surgical intensive care unit 2018-06-22 anticipated 90 Complete https://irct.ir/trial/33254 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients who are eligible to participate will be assigned a code. Afterward, the participants will be allocated to the intervention group or the control group using the table of random numbers, Blinding description: In addition to the participants themselves who are unaware of the intervention they receive, data collector and data analyzer are also both blinded to the allocated groups. 1-2 ventilator-associated pneumonia. Intervention 1: Control group (routine): Individuals undergo antibiotic therapy and closed suction using a 50-cc normal sterile saline on a daily basis. Intervention 2: Intervention group (bronchoscopic suction): Patients will undergo bronchoscopic suction every other day in addition to the treatment received by the control group. Yes - There is a plan to make this available What will be shared: Deidentified Individual Participant Data Set When: after the paper extracted from the study is published and for 6 months To whom: researchers Conditions: research purposes Where to obtain: email How to obtain: email to the corresponding author Comments:
public Maryam Bayati
Ghaffari Ave.
Birjand Iran (Islamic Republic of) 9717853577 +98 32233019 Xenon1346@gmail.com Birjand University of Medical Sciences scientific Dr Hasan Karbasi
Ghaffari Ave.
Birjand Iran (Islamic Republic of) 9717853577 +98 56 3239 5600 Xenon1346@gmail.com Birjand University of Medical Sciences Iran (Islamic Republic of) Diagnosis of ventilator-associated pneumonia after 48 hours of mechanical ventilation Informed consent for participation in the study no limit no limit Both Pregnancy Infliction with pneumonia before intubation or 48 hours before intubation Antibiotic use before intubation Suffering from diseases that reduce immunity level Use of immunosuppressant drugs Patients with neutropenia (less than or equal to 500 neutrophils per milliliter) J12.8 Other viral pneumonia Treatment - Other Treatment - Devices Control group (routine): Individuals undergo antibiotic therapy and closed suction using a 50-cc normal sterile saline on a daily basis. Intervention group (bronchoscopic suction): Patients will undergo bronchoscopic suction every other day in addition to the treatment received by the control group. Improvement status according to APACHI II criteria. Timepoint: daily. Method of measurement: APACHI II checklist. Temperature. Timepoint: every 3 hours daily for a maximum of 10 days. Method of measurement: thermometer. Number of blood leukocytes. Timepoint: on a daily basis. Method of measurement: laboratory results. Blood oxygenation status. Timepoint: on a daily basis. Method of measurement: arterial blood gas test. Tracheal aspirate culture. Timepoint: at baseline and on completion day of study. Method of measurement: laboratory results. Mortality. Timepoint: on a daily basis for 10 days. Method of measurement: observation. Birjand University of Medical Sciences Approved 2017-09-12 Ethics Committee of Birjand University of Medical Sciences Birjand University of Medical Sciences, Ayatollah Ghaffari Street Birjand South Khorasan Iran (Islamic Republic of)