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IRCT20180805040711N1 IRCT 2018-09-15 Tabriz University of Medical Sciences The effect of Probiotics in the prevention of diarrhea caused by antibiotics Comparison of the effect of probiotics on the prevention of diarrhea in two groups of patients treated with antibiotics and patients treated with antibiotics and probiotics 2017-04-04 anticipated 300 Complete https://irct.ir/trial/33281 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The sampling method will be simple random. The samples will be randomly divided by random numbers into two groups of intervention group and placebo group (150 in each group), Blinding description: The study will be done as a single-blind form. The Probiotic drug used in this design is a capsule containing Saccharomyces Cerevisiae brand Yomogi 250 mg. In the control group, 250 mg of lactose-free dry milk will be used in capsules similar to the Probiotic capsules. Capsules will be packaged and coded. Samples are divided into groups of intervention group and placebo group by random numbers. Patients are blinded about taking the medication or placebo, and they will not know the contents of the pack (medication or placebo). 3 Diarrhea caused by antibiotics. Intervention 1: Intervention group: The Probiotic drug capsule containing Saccharomyces cerevisiae brand Yomogi 250 mg. Intervention 2: Control group: 250 mg of lactose-free dry milk will be used in capsules similar to the Probiotic capsule. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Dr.Seyed Mehdi Haghdoost
Medicine Faculity, Ghoghasht Ave, Tabriz City
Tabriz Iran (Islamic Republic of) 5165687386 +98 41 3334 1249 haghdustm@tbzmed.ac.ir Tabriz University of Medical Sciences scientific Dr.Seyed Mehdi Haghdoost
Medicine Faculity, Ghoghasht Ave, Tabriz City
Tabriz Iran (Islamic Republic of) 5165687386 +98 41 3334 1249 haghdustm@tbzmed.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Iran (Islamic Republic of) The age range is 18-94 years Need to get antibiotics for any cause Conscious Consciousness of Patients to Participate in the Study 18 years 94 years Both Patients with diarrhea at the time of admission Patients with any pathological illness that causes diarrhea History of intestinal surgery Rheumatism and endocarditis Patients treated with laxative Patients who have had antibiotic use in the last 2 weeks Patients with artificial valve and immune deficiency K59.1 Functional diarrhea Prevention Placebo Intervention group: The Probiotic drug capsule containing Saccharomyces cerevisiae brand Yomogi 250 mg Control group: 250 mg of lactose-free dry milk will be used in capsules similar to the Probiotic capsule The volume and frequency of antibiotic-induced diarrhea. Timepoint: The beginning of the treatment (before the intervention), during and two weeks after treatment. Method of measurement: Checklist designed in the study (The frequency of diarrhea is over 3 times and the volume of diarrhea is about 200 grams per day). Tabriz University of Medical Sciences Approved 2018-07-23 Ethics committee of Tabriz University of Medical Science (Human Subjects Studies) Gholghasht Ave, Tabriz City Tabriz East Azarbaijan Iran (Islamic Republic of)