IRCT20170517034008N1 IRCT 2019-04-07 Shiraz University of Medical Sciences Effect of hypertonic saline injection in diabetic neuropathy Efficacy of perineural hypertonic saline injection versus acupoints of foot in the management of diabetic neuropathy: a randomized clinical trial 2019-04-09 anticipated 30 Complete https://irct.ir/trial/33558 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Thirty eligible patients will be randomly allocated to two parallel groups (Perineural injection group or G1 and acupoints injection group or G2). Randomization sequence is created using Excel 2007 (Microsoft) with a random block size of six, Blinding description: We will perform a double blinded study. In both groups there are equal volume and appearance of the drug and the patients have no ideas about injection sites of the groups. Also the analyst does not have any knowledge about the type of intervention in each group. 3 Diabetic neuropathy. Intervention 1: Intervention group 1: The study solution consisted of 5 mL sodium chloride hypertonic 5% and 1 mL lidocaine 2% (Pasteur institute of Iran) was injected with a 27-gauge needle near the tibial, saphenous and sural nerves (based on anatomical landmarks) under sterile condition.(Two milliliters of the study solution were injected in each point.). Intervention 2: Intervention group 2: we defined three acupuncture points based on the relevant literature, including ST-41, ST-44 and GB-40.The study solution consisted of 5 mL sodium chloride hypertonic 5% and 1 mL lidocaine 2% (Pasteur institute of Iran) was injected with a 27-gauge needle and two milliliters in each point. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information