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IRCT20150217021121N3 IRCT 2018-09-18 Tabriz University of Medical Sciences Dexmedetomidine after laparotomy surgery Effect of intravenous dexmedetomidine on control of blood pressure after laparotomy surgery in hypertensive patients 2017-06-25 anticipated 76 Complete https://irct.ir/trial/33577 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: To randomly divide the patients into two groups, Random Allocation Software was used.And the patients were divided into two groups of control and medication, Blinding description: The surgeon and the patient do not know the type of group in this study, but the anesthetist knows about this study and the drugs and after examining the case number and the patient's name and medications will checked. 2-3 Blood pressure after laparotomy surgery in hypertensive patients. Intervention 1: Intervention group: In the patients studied group ,15 minutes before the end of surgery (starting to close the abdomen) 0.5 mic g / kg dexmedetomidine diluted in 5 ml of normal saline , slowly IV injected . Intervention 2: Control group: In the control group ,15 minutes before the end of surgery (starting to close the abdomen) only 5 ml of normal saline , slowly IV , injected. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The publication plan is still unknown
public Dr Reza Movassaghi
Department of Anesthesiology, Faculty of Medicine,Tabriz University of Medical sciences
Tabriz Iran (Islamic Republic of) 5165665931 +98 41 3336 8740 rz_movassaghi@yahoo.com Tabriz University of Medical Sciences scientific Dr Reza Movassaghi gargari
Department of Anesthesiology, Faculty of Medicine,Tabriz University of Medical sciences
Tabriz Iran (Islamic Republic of) 5165665931 0098‭ 41 33368740 rz_movassaghi@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) History of hypertension Candidate for elective laparotomy 18 years 70 years Both Age under 18 and over 70 years old Addiction Severe systemic disabling Mental illness and chronic pain disorders Patients with ASA class III and more and patient refusal I10 Hypertension Prevention Prevention Intervention group: In the patients studied group ,15 minutes before the end of surgery (starting to close the abdomen) 0.5 mic g / kg dexmedetomidine diluted in 5 ml of normal saline , slowly IV injected . Control group: In the control group ,15 minutes before the end of surgery (starting to close the abdomen) only 5 ml of normal saline , slowly IV , injected. Controlling of blood pressure after laparotomy surgery in hypertensive patients. Timepoint: It is first recorded every 15 minutes (up to 2 hours) and then every 2 hours after the operation. Method of measurement: Mercury pressure gauge device. Tabriz University of Medical Sciences Approved 2018-07-23 Ethics committee of Tabriz University of Medical Sciences Imam Reza Hospital Golghasht Ave. Tabriz East Azarbaijan Iran (Islamic Republic of)