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IRCT20180912041018N1 IRCT 2018-10-13 Semnan University Effect of Eight Weeks Anaerobic Interval Training on Irisin, Insulin and Lipid Profiles in Elderly Men Effect of Eight Weeks Anaerobic Interval Training on Irisin, Insulin and Lipid Profiles in Elderly Men 2018-09-23 anticipated 30 Complete https://irct.ir/trial/33837 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Basic scienece, Randomization description: The subjects using NCSS PASS11 software, Procedure menu, DOE submenu, will be randomly divided into two groups. N/A aging. Intervention 1: Intervention group: The intervention group performed anaerobic interval training, which included 10 repetitions of 20 seconds running, 70-80% heart rate and 80 second active rest between repetitions for eight weeks and six sessions per week. Exercise intensity was determined by heart rate and controlled by the researcher using polar-pulse meter. The subjects initially began to warm up and stretch for seven minutes, and at the end they cooled down for five to ten minutes. In order to comply with the Overload Principle, one repetition was added to the volume of exercise each week until the eighth week when the repetitions reached 17 times in each session. Intervention 2: The control group was under routine care and had similar conditions to the intervention group without participating in the exercise protocol. Yes - There is a plan to make this available What will be shared: Only the information of original outcome to be shared. When: 6 month after published paper. To whom: Resercher Conditions: For writing review article Where to obtain: rhm@semnan.ac.ir How to obtain: After receiving mail Comments:
public Rouhollah Haghshenas
Standard Square
Semnan Iran (Islamic Republic of) 35131-19111 +98 23 3336 3494 rhm@semnan.ac.ir Semnan University scientific Rouhollah Haghshenas
Standard Square
Semnan Iran (Islamic Republic of) 35131-19111 +98 23 3336 3494 rhm@semnan.ac.ir Semnan University Iran (Islamic Republic of) Being committed to the program Age range 58-70 years Ability to execute the training protocol Committed to doing the program 58 years 70 years Male perform regular exercise in 45 days ago are takeing certain medications in the last 3 months (Steroid drugs such as cortisone, nandrolone and ....) smoking and alcohol consumption Having acute illness (acute articular disease and bone softness, bone fractures) Rehabilitation Lifestyle Intervention group: The intervention group performed anaerobic interval training, which included 10 repetitions of 20 seconds running, 70-80% heart rate and 80 second active rest between repetitions for eight weeks and six sessions per week. Exercise intensity was determined by heart rate and controlled by the researcher using polar-pulse meter. The subjects initially began to warm up and stretch for seven minutes, and at the end they cooled down for five to ten minutes. In order to comply with the Overload Principle, one repetition was added to the volume of exercise each week until the eighth week when the repetitions reached 17 times in each session. The control group was under routine care and had similar conditions to the intervention group without participating in the exercise protocol. Irisin serum level. Timepoint: before the start of the exercise protocol and 48 hours after the last exercise session, 5 ml of blood samples were taken from the ventricle of the left arm while sitting and after 12 o'clock fasting. Method of measurement: To measure serum levels of Irisin, a special human-grade Irisin kit for the crystalline made in China was used with sensitivity of 0.1 μm and according to ELISA method and in accordance with the instructions for the kit. Lipid profiles. Timepoint: before the start of the exercise protocol and 48 hours after the last exercise session, 5 ml of blood samples were taken from the ventricle of the left arm while sitting and after 12 o'clock fasting. Method of measurement: Lipid profiles (LDL, HDL and FBS) were also measured using Pars Azmon kit. Semnan University Approved 2017-07-12 Ethics committee of semnan university of medical sciences Standard Square Semnan Semnan Iran (Islamic Republic of)