]>
IRCT20180915041037N1 IRCT 2018-11-11 Yazd University of Medical Sciences The effect of antibiotic therapy on the results of biopsy in men The effect of antibiotic therapy on the results of biopsy in asymptomatic men older than 40 years of age with PSA above 4 ng/ml 2018-10-23 anticipated 80 Complete https://irct.ir/trial/33867 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients are randomly assigned to intervention and control groups using sealed envelopes. 3 Prostate Cancer. Intervention 1: Intervention group: Patients will undergo antibiotic therapy (Ciprofloxacin tablets 500 mg every 12 hours for 4 weeks). Intervention 2: Control group: Patients won't undergo any medication. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.
public Hadi Maleki
Farrokhi Street
Yazd Iran (Islamic Republic of) 8913893111 +98 35 3626 0000 hadi.maleki88@gmail.com Yazd University of Medical Sciences scientific Samd Zare
Farrokhi Street
Yazd Iran (Islamic Republic of) 8913893111 +98 35 3626 0000 drzaree@yahoo.com Yazd University of Medical Sciences Iran (Islamic Republic of) Patients older than 40 years of age with prostate-specific antigen (PSA) in the range of 4-15 ng/ml Patients with normal digital rectal examination (DRE) Patients without Irritative and obstructive urinary symptoms Patients with informed consent 40 years 70 years Male Patients undergoing rectal biopsy (TRUS) during the past month. Patients who have ejaculation in the past 28 hours. Patients who have undergone urological surgeries during the past six months. Patients with a history of prostate cancer or clinical and laboratory evidence Patients with a history of taking 5-alpha-blockers such as Finasteride in the past six weeks C61 Malignant neoplasm of prostate Treatment - Drugs Treatment - Drugs Intervention group: Patients will undergo antibiotic therapy (Ciprofloxacin tablets 500 mg every 12 hours for 4 weeks) Control group: Patients won't undergo any medication. PSA levels above 4 ng / ml. Timepoint: One month after referring to the specialist. Method of measurement: Blood test. Biopsy results. Timepoint: One month after referring to the specialist. Method of measurement: Standard biopsy (12-core). Yazd University of Medical Sciences Approved 2018-10-27 Ethics committee of Yazd Shahid Sadoughi University of Medical Sciences Bahonar Square Yazd Yazd Iran (Islamic Republic of)