]>
IRCT20180416039326N7 IRCT 2019-05-31 Esfahan University of Medical Sciences Effect of intranasal dexamethasone on prevention of postoperative sore throat The prophylactic effect of intranasal dexamethasone on the postoperative sore throat 2019-06-08 anticipated 80 Complete https://irct.ir/trial/34034 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Random allocation to intervention and control groups using a random number table, Blinding description: In this double-blind clinical trial after induction of anesthesia and 30 seconds before the tracheal intubation In the intervention group, dexamethasone (2 ml) and in the control group normal saline (2 ml) will be prescribed via the nostril. 2 sore throat. Intervention 1: Intervention group: After receiving 5 ml / kg of ringer lactate and pre-oxygenation for patients, the same anesthetic induction was performed including Fentanyl 2mcg / kg, Thiopental sodium 5 mg / kg and Atracurium 0.6mg / kg, and the patients underwent mechanical ventilation by mask for three minutes.Immediately before intubation, 4 mg of dexamethasone was injected intra-nasal. Intervention 2: Control group: After receiving 5 ml / kg of ringer lactate and pre-oxygenation for patients, the same anesthetic induction was performed including Fentanyl 2mcg / kg, Thiopental sodium 5 mg / kg and Atracurium 0.6mg / kg, and the patients underwent mechanical ventilation by mask for three minutes.Immediately before intubation, 4 mg of normal salin was injected intra-nasal. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is no more information
public hamidreza shetabi
Feyz Hospital ،modares st
Isfahan Iran (Islamic Republic of) 73461-81764 +98 31 3445 2034 hamidshetabi@med.mui.ac.ir Esfahan University of Medical Sciences scientific Hamidreza Shetabi
Feiz hospital, modarres St
Isfahan Iran (Islamic Republic of) 73461-81764 +98 31 3668 8138 hamidshetabi@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) candidate for eye surgery Age between 18-75 desire to participate in study American Society of Anesthesiologists(ASA) Physical Status Classification 1or 2 18 years 75 years Both mental disorders Active upper respiratory tract infection Alcohol or opioid addiction Allergies to used drugs History of Recent Corteon Therapy History of chronic use of sedative medicines Severe obstructive pulmonary disease and asthma The occurrence of any anesthetic induction supply More than once trying to incubate Prolonged intubation time Use laryngeal mask Other spec T88.8 Prevention Placebo Intervention group: After receiving 5 ml / kg of ringer lactate and pre-oxygenation for patients, the same anesthetic induction was performed including Fentanyl 2mcg / kg, Thiopental sodium 5 mg / kg and Atracurium 0.6mg / kg, and the patients underwent mechanical ventilation by mask for three minutes.Immediately before intubation, 4 mg of dexamethasone was injected intra-nasal Control group: After receiving 5 ml / kg of ringer lactate and pre-oxygenation for patients, the same anesthetic induction was performed including Fentanyl 2mcg / kg, Thiopental sodium 5 mg / kg and Atracurium 0.6mg / kg, and the patients underwent mechanical ventilation by mask for three minutes.Immediately before intubation, 4 mg of normal salin was injected intra-nasal. Sore throat. Timepoint: hours 0,2,4and6 after intubation. Method of measurement: scoring system for sore throat,cough and hoarseness. Hoarseness. Timepoint: hours 0,2,4and6 after intubation. Method of measurement: scoring system for sore throat,cough and hoarseness. Cough. Timepoint: hours 0,2,4and6 after intubation. Method of measurement: scoring system for sore throat,cough and hoarseness. Oxygen saturation percentage. Timepoint: hours 0,2,4and6 after intubation. Method of measurement: Pulse oximetry. Esfahan University of Medical Sciences Approved 2019-03-19 Ethics Committee of Isfahan University of Medical Sciences Hezar Jerib BLVD Esfahan Isfehan Iran (Islamic Republic of)