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IRCT20180923041092N1 IRCT 2019-11-23 Islamic Azad University effect of Thymus Vulgaris essential oil on Candida albicans Clinical comparison of the effect of Thymus Vulgaris essential oil and Chlorhexidine on Candida albicans accumulated on orthodontic removable plaques 2019-04-20 anticipated 30 Complete https://irct.ir/trial/34180 interventional Randomization: Not randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Blinding description: Participants and all researchers except that person who determines code to the solutions are blind in this study. Only one researcher who determines color code to the solutions, does not play a role in collecting data is not blind in this study. N/A In the present study, to find the desired sample size, a number of patients with removable orthodontic plaque in a private clinic were randomly selected. Before starting the study, an interview was conducted with them to evaluate their dental and medical history, oral health status, occlusion and proper dental care and their health status. Of the 43 patients who were sampled, those who had one of the following were excluded from the study, and 36 who were eligible for inclusion in the study were selected for further studies: - No Candida albicans on Orthodontic removable plaque-Large diastema-Periodontal problem-Use Antimicrobial mouthwash-Antibiotic use in the last 3 months-Very poor oral hygiene. Intervention 1: Intervention group: Participants in intervention group obtained a solution containing thymus vulgaris 2%. They were asked to spray solutions on to an orthodontic removable appliance.Swab from three specific of removable orthodontic appliance were taken three times: 1.At the beginning of study. 2. After two days. 3. After 5 five days. Intervention 2: Control group: Participants in control group obtained a solution containing Chlorhexidine 0/2%. They were asked to spray solutions on to an orthodontic removable appliance. Swab from three specific of removable orthodontic appliance were taken three times:1. At the beginning of study2. After two days3. After 5 five days. Yes - There is a plan to make this available What will be shared: Classification of individuals based on the number of Candida albicans grown colonies in three sampling times (Before spraying 2% Thymus Vulgaris essential oil and Chlorhexidine 0.2%, two days and then five days after spraying) When: Start of access period 6 months after printing results To whom: Every one Conditions: No one is allowed to work on our data Where to obtain: send Email to T-baheri@yahoo.com and announce the request. How to obtain: send Email to T-baheri@yahoo.com and announce the request. Comments:
public Tahereh Baheri Moghadam
3th Floor, medical Bldg, 11 Alley, Sattar Khan Ave.
Shiraz Iran (Islamic Republic of) 71847-35716 +98 71 3649 1415 T_baheri@yahoo.com Islamic Azad University scientific Navid Naseri
3th floor, medical Bldg, 11 Alley, Sattar Khan Ave.
Shiraz Iran (Islamic Republic of) 71847-35716 +98 71 3649 1415 T_baheri@yahoo.com Islamic Azad University Iran (Islamic Republic of) patients with expansion orthodontic appliance 7 years 12 years Both Moderate to Severe Crowding and Irregularity Periodontal Problem Usage of Antimicrobial Mouth Watch Antibiotic therapy within 90 days poor oral hygiene History of rheumatic fever, History of diabetes, hepatic, renal and immune system disease Treatment - Drugs Treatment - Drugs Intervention group: Participants in intervention group obtained a solution containing thymus vulgaris 2%. They were asked to spray solutions on to an orthodontic removable appliance.Swab from three specific of removable orthodontic appliance were taken three times: 1.At the beginning of study. 2. After two days. 3. After 5 five days. Control group: Participants in control group obtained a solution containing Chlorhexidine 0/2%. They were asked to spray solutions on to an orthodontic removable appliance. Swab from three specific of removable orthodontic appliance were taken three times:1. At the beginning of study2. After two days3. After 5 five days Percentage of people with Candida albicans on orthodontic removable plaque and Clinical comparison of the effect of Zataria Multiflora essential oil and Chlorhexidine on Candida albicans accumulated on orthodontic removable plaques. Timepoint: Sampling and Count of Candida albicans colonies at the beginning of the study (before intervention), 2 and 5 days after spraying with 2%Zataria Multiflora essential oil and chlorhexidine. Method of measurement: Incubator, Autoclave, Optical Microscope - Ultrasonic Bathroom. Islamic Azad University Approved 2019-02-27 Ethics committee of Azad University of Shiraz School of Dentistry, Shiraz Azad University, North ghaani Ave. Shiraz Fars Iran (Islamic Republic of)