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IRCT20180306038978N1 IRCT 2019-05-28 Bandare-abbas University of Medical Sciences The effect of cardiac remote ischemic preconditioning (IRPC) on the release of cardiac troponin I after elective percutaneous coronary intervention (PCI) The effect of cardiac remote ischemic preconditioning (IRPC) on the release of cardiac troponin I after elective percutaneous coronary intervention (PCI) in outpatients admitted to the angiography ward 2018-10-06 anticipated 240 Complete https://irct.ir/trial/34206 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Subjects were randomized into two groups by means of a randomization table acquired from the Random Allocation software. for example: 0001: Control 0041: Case 0081: Case 0121: Case 0161: Control 0201: Case. N/A Ischemic heart disease. Intervention 1: Intervention group: An hour before percutaneous coronary intervention a blood pressure cuff will be placed around the non-dominant arm of the patients, then it will be inflated up to 200 mmHg for 5 minutes, afterwards the cuff will be deflated for 5 minutes and this cycle will be repeated two more times. Intervention 2: Control group: An hour before percutaneous coronary intervention deflated blood pressure cuff will be placed on the non-dominant arm of the patients for 30 minutes. Yes - There is a plan to make this available What will be shared: Primary outcome and demographic data When: Starting 1 year after publication of the results To whom: Researchers working in academic institutions Conditions: Only analyses not indicated in the published article are allowed. Where to obtain: Applicants can use the following email address to submit their requests and an SPSS data file will be available to them. shoeibpaskhandi@yahoo.com How to obtain: Valid identification card indicating that the applicant is a member of academic institutions Comments:
public Shoeib Paskhandi
Bandar Abbas Faculty of Medicine, Imam Hossein Blvd., Hormozgan, Iran
Bandar Abbas Iran (Islamic Republic of) 7919693116 +98 76 3371 0370 hums@hums.ac.ir Bandare-abbas University of Medical Sciences scientific Shoeib Paskhandi
Bandar Abbas Faculty of Medicine, Imam Hossein Blvd., Bandar Abbas, Hormozgan, Iran
Bandar Abbas Iran (Islamic Republic of) 7919693116 +98 76 3371 0370 hums@hums.ac.ir Bandare-abbas University of Medical Sciences Iran (Islamic Republic of) Age of 18 years or older Stable coronary artery disease Requirement of elective PCI 18 years no limit Both Emergency PCI Renal dysfucntion High cardiac troponin levels before PCI Women of childbearing age Use of Nicorandil or Glibenclamide Severe comorbidities (terminal illnesses, advanced cancers with low life expectancy, renal failure, hepatic failure, rheumatic diseases) I24.9 Acute ischemic heart disease, unspecified Prevention Placebo Intervention group: An hour before percutaneous coronary intervention a blood pressure cuff will be placed around the non-dominant arm of the patients, then it will be inflated up to 200 mmHg for 5 minutes, afterwards the cuff will be deflated for 5 minutes and this cycle will be repeated two more times. Control group: An hour before percutaneous coronary intervention deflated blood pressure cuff will be placed on the non-dominant arm of the patients for 30 minutes. Cardiac troponin I. Timepoint: Cardiac troponin I is measured right before and 18 hours after percutaneous coronary intervention. Method of measurement: Quantitative measurement of cardiac troponin I using enzymatic method. Bandare-abbas University of Medical Sciences Approved 2018-03-06 Ethics Committee of Hormozgan University of Medical Sciences Jomhouri Eslami Blvd, Shahid Mohammadi Hospital, Bandar Abbas Bandar Abbas Hormozgan Iran (Islamic Republic of)