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IRCT20170419033535N4 IRCT 2019-01-05 Islamic Azad University Effect of Freeze-Dried Bone Allograft on new bone formation after tooth extraction Effect of Healing Time on New Bone Formation after Tooth Extraction with Freeze-Dried Bone Allograft 2017-10-22 anticipated 40 Complete https://irct.ir/trial/34704 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Dividing the samples completely randomly into two groups of 3 months (Intervention group) and 4 months (Control group) by dropping the coin and hiding the card until the patients were recalled, Blinding description: All individuals involved in this research, such as Clinicians, Outcome Evaluators, Data Analyzers, Safety Committees, and Data Monitoring, have been unaware of the randomization process of samples, and only researchers and therapists in this study have compared the time Sampling and referral of patients are well known. N/A Evaluation of bone formation with FDBA after tooth extraction.. Intervention 1: Intervention group: This group includes 20 dental samples need to be extracted and required Implant treatment. The dental socket (after tooth extraction) is filled with FDBA, from Hamanand Saz Baft Kish company, Iran, and its entry is covered with Collagen from brand called Auto Plug. The specimens are randomly divided into this group (3 months) and after the prescribed time, they are called for sampling. The bone sample is taken to examine the condition of the bone and is delivered to the Pathology Laboratory. FDBA (Freeze-Dried bone Allograft) is an Allograft material that is obtained by Minerilizing the cortical bone of the same species, and freezing and drying it. In 1976, FDBA entered periodontal treatments and was considered as an Osteoconductive material. Intervention 2: Control group: This group includes 20 dental samples need to be extracted and required implant treatment. The dental socket (after tooth extraction) is filled with FDBA, from Hamanand Saz Baft Kish company, Iran, and its entry is covered with Collagen from brand called Auto Plug. The specimens are randomly divided into this group (4 months) , and after the prescribed time, they are called for sampling. The bone sample is taken to examine the condition of the bone and is delivered to the Pathology Laboratory. FDBA (Freeze-Dried bone Allograft) is an Allograft material that is obtained by Minerilizing the cortical bone of the same species, and freezing and drying it. In 1976, FDBA entered periodontal treatments and was considered as an Osteoconductive material. Yes - There is a plan to make this available What will be shared: Comparison of short-term effects (3 months, intervention group) and long-term effects (4 months, control group) of FDBA application on Histopathology of bone formation following tooth extraction in patients referring to dental unit of Islamic Azad University of Tehran in 1396-1397. When: 6 months after printing results To whom: All people who need data can apply for them. Conditions: Analyzes that do not harm our data. Where to obtain: Faculty of Dentistry Islamic Azad University of Tehran How to obtain: Visit the Faculty of Dentistry, Islamic Azad University of Tehran and request there, and will access the data within 1 week. Comments:
public Omid Moghadas
Ninth Neyestan Avenue, Pasdaran Street, Tehran, Iran.
Tehran Iran (Islamic Republic of) 1946853314 +98 21 2256 4571 o_moghaddas@dentaliau.ac.ir Islamic Azad University scientific Omid Moghadas
Ninth Neyestan Avenue, Pasdaran Street, Tehran.
Tehran Iran (Islamic Republic of) 1946853314 +98 21 2256 4571 o_moghaddas@dentaliau.ac.ir Islamic Azad University Iran (Islamic Republic of) Single-rooted teeth needing extraction Patient desiring restoration with Dental implant Adequate space for Restoration no limit no limit Both Patients not fulfilling inclusion criteria or not compliant with necessary procedural follow-up Active Systemic/Local infection not including Periodontitis Medical conditions or medications known to alter soft tissue or bony healing (Poorly controlled Diabetes Mellitus [DM], Bisphosphonates, Immunosuppressives, etc.) Teeth with short roots or roots that were Malpositioned such that the Core Biopsy might include bone along the Socket Wall. Females of childbearing age without Tubal Ligation, Menopause, or Hysterectomy were required to have a Negative Pregnancy Test prior to Surgery. Pregnancy K08.2 Atrophy of edentulous alveolar ridge Treatment - Surgery Treatment - Surgery Intervention group: This group includes 20 dental samples need to be extracted and required Implant treatment. The dental socket (after tooth extraction) is filled with FDBA, from Hamanand Saz Baft Kish company, Iran, and its entry is covered with Collagen from brand called Auto Plug. The specimens are randomly divided into this group (3 months) and after the prescribed time, they are called for sampling. The bone sample is taken to examine the condition of the bone and is delivered to the Pathology Laboratory. FDBA (Freeze-Dried bone Allograft) is an Allograft material that is obtained by Minerilizing the cortical bone of the same species, and freezing and drying it. In 1976, FDBA entered periodontal treatments and was considered as an Osteoconductive material. Control group: This group includes 20 dental samples need to be extracted and required implant treatment. The dental socket (after tooth extraction) is filled with FDBA, from Hamanand Saz Baft Kish company, Iran, and its entry is covered with Collagen from brand called Auto Plug. The specimens are randomly divided into this group (4 months) , and after the prescribed time, they are called for sampling. The bone sample is taken to examine the condition of the bone and is delivered to the Pathology Laboratory. FDBA (Freeze-Dried bone Allograft) is an Allograft material that is obtained by Minerilizing the cortical bone of the same species, and freezing and drying it. In 1976, FDBA entered periodontal treatments and was considered as an Osteoconductive material. The amount of Bone Formation. Timepoint: 3 months and 4 months. Method of measurement: Calculated by Optical Microscope. The amount of Residual Graft. Timepoint: 3 months and 4 months. Method of measurement: Calculated by Optical Microscope. The amount of Connective Tissue and Inflammation Rate. Timepoint: 3 months and 4 months. Method of measurement: Calculated by Optical Microscope. Islamic Azad University Approved 2017-06-18 Faculty of Dentistry Islamic Azad University of Tehran Ninth Neyestan Avenue, Pasdaran Street, Tehran, Iran. Tehran Tehran Iran (Islamic Republic of)