IRCT20181030041500N1 IRCT 2019-04-30 Rafsanjan University of Medical Sciences Topical effect of cicer arientinumr extract on some clinical signs of knee osteoarthritis Topical effect of cicer arientinumr extract on some clinical signs of knee osteoarthritis: a randomized and double blind clinical trial 2017-09-23 anticipated 75 Complete https://irct.ir/trial/34970 interventional Randomization: Not randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Blinding description: for double blind study creating, before the study begins, the drugs will be enclosed by someone ( not researcher ) in the same packages and encoded in A, B, and C. Rheumatologist prescribed as either A or B or C which drug delivery is done by another person. Assessment of clinical symptoms is done by a resident who is not aware of the type of drug consumption. 3 osteoarthritis. Intervention 1: Intervention group: Group B: topically received cicer arientinumr extraction twice a day for three months. Patients in all three groups can use oral drugs to relieve pain in the same way. Intervention 2: Control group: Group C: topically received Paraffin ( placebo) twice a day for three months for comparing the effects of other groups. Patients in all three groups can use oral drugs to relieve pain in the same way. Intervention 3: Intervention group: Group A: Topically received piroxicam gel for twice a day for 3 months. Patients in all three groups can use oral drugs to relieve pain in the same way. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to time shortage, I didn’t make decisions yet