]>
IRCT20181031041519N1 IRCT 2019-01-06 Iran University of Medical Sciences The effect of Myo-inositol on the treatment of male infertility in couples under IUI Effect of Myo-inositol on Sperm Parameters and Fertility Rate in Patients with Oligoasthenospermia Treated with IUI: A Randomized Clinical Trial 2017-03-20 anticipated 60 Complete https://irct.ir/trial/34979 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: - Patients were randomly divided into two groups using Excel software - We used stratified randomization - Each code contained in sealed envelopes was provided to clinical care, Blinding description: Patients are divided into two groups of case and control according to the random numbers table, and patient, the physician and responsible for examining the sperm parameters didnt know which sample containing or not containing inositol. 3 Male infertility due to oligoastenospermia. Intervention 1: Semen sample removed after 48-72h from the ejaculation method and then placed in a 37-degree incubator for 30 minutes. After liquefying the sample, the sperm analysis with gradient method (sill select plus)After the sperm separation step, the subjects were randomly divided into two groups. Intervention Group: in the semen of this group, add .5 milliliter of myoinositol at a concentration of 2 mg/ml and incubate for 37 °C in the incubator for 2 hours. Intervention 2: Control group: Semen sample removed after 48-72h from the ejaculation method and then placed in a 37-degree incubator for 30 minutes. After liquefying the sample, the sperm analysis with gradient method (sill select plus)After the sperm separation step, the subjects were randomly divided into two groups. Control Group: in the semen of this group not add myoinositol, but only incubate for 37 °C in the incubator for 2 hours. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I will decide upon the completion of the residency
public Seyyedeh Tahereh Ghazi mirsaeed
no8.colop 18 Ally.imam montazer St.Satarkhan St
tehran Iran (Islamic Republic of) 1444933611 +98 21 8826 5089 dr.ghazi83@gmail.com Iran University of Medical Sciences scientific dr.zahra doroodian
Rasul akram Hospital Satarkhan St
tehran Iran (Islamic Republic of) 1445613131 +98 21 6655 9595 dr.ghazi83@gmail.com Iran University of Medical Sciences Iran (Islamic Republic of) Couples who have not been pregnant for one year In the studies included hysterosalpingography and hormonal testing all women were uncomplicated Men have oligo or asthenospermia. no limit 38 years Both Sever male factor (Oligo Stoenou men) Untreated hormonal problem BMI higher than 35 The age of a woman is over 38 years old N46 Male infertility Treatment - Drugs Treatment - Drugs Semen sample removed after 48-72h from the ejaculation method and then placed in a 37-degree incubator for 30 minutes. After liquefying the sample, the sperm analysis with gradient method (sill select plus)After the sperm separation step, the subjects were randomly divided into two groups. Intervention Group: in the semen of this group, add .5 milliliter of myoinositol at a concentration of 2 mg/ml and incubate for 37 °C in the incubator for 2 hours. Control group: Semen sample removed after 48-72h from the ejaculation method and then placed in a 37-degree incubator for 30 minutes. After liquefying the sample, the sperm analysis with gradient method (sill select plus)After the sperm separation step, the subjects were randomly divided into two groups. Control Group: in the semen of this group not add myoinositol, but only incubate for 37 °C in the incubator for 2 hours. Sperm motility Morphology Agglutination Volume Acidity Duration of liquefaction Dfi. Timepoint: sperm sample day After sample incubation Two hours after treatment with myo-inositol. Method of measurement: Examination of sperm samples under a microscope. Fertility. Timepoint: Two weeks after iui. Method of measurement: Serum Beta HCG. Iran University of Medical Sciences Approved 2017-11-21 Ethics Committee of Iran University of Medical Sciences Iran University of Medical Sciences.Hemmat Ave.Tehran Town tehran Tehran Iran (Islamic Republic of)