<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20181124041744N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2018-12-30</date_registration>
      <primary_sponsor>IAU, Varamin</primary_sponsor>
      <public_title>The effect of exercise and L Citrulline Malate on NO and GH</public_title>
      <acronym></acronym>
      <scientific_title>Effect of an endurance, resistant exercise course with L Citrulline Malate supplementation On NO and GH in young Wrestlers</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2018-12-06</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>40</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/35421</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Factorial, Purpose: Basic scienece, Other design features: Exercise and Supplement, Exercise, Supplement, control A clinical trial with a control group, with parallel groups, has been randomized The sample size is 10 people in each group, Randomization description: Individual The statistical sample 190 consists of members of the sports clubs of the provincial capital، They were selected randomly، and had the requirements set out in the descriptive questionnaire Their names were the same on the same sheets and among them 40 papers by an unrelated person was selected by research Of course, the names of the people were people they had the requirements set out in the descriptive questionnaire, there were physical and health conditions and sports.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Relation between Endurance, Resistance exercise course with L Citrulline Malate Supplementation on NO and GH in young Wrestlers.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group 1: L Citrulline Malate, Blood sampling for pretest immediately before starting the activity from each participate resistance and Supplements 3 grams per day for 60 days. endurance training program for 8 weeks and blood sampling at the end of the research. L Citrulline Malate Supplements of Hungarian Scitec company, 90 Kaspeln Citrulline Malate 3000 mg pro Portion. Intervention 2: Intervention group 2:  Only practice (The protocol is similar to 1) Resistance, endurance training program for 8 weeks. Intervention 3: Intervention group 3: Only supplements (The protocol is similar to 1) Supplements 3 grams per day For 60 days. Blood sampling at the end of the research. L Citrulline Malate Supplements of Hungarian Scitec company, 90 Kaspeln Citrulline Malate 3000 mg pro Portion. Intervention 4: Control group 4: No training and supplementation.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There Is Not More Information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Farshad Varjavand</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No 14, Shiyan Building, Eskandari Alley, Taleghani Ave</address>
        <city>Varamin</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>3371774031</zip>
        <telephone>+98 21 3627 2909</telephone>
        <email>varjavand@hotmail.com</email>
        <affiliation>Ministry of Cooperatives, Labor, and Social Affairs</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Farshad Varjavand</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No 14, Shiyan Building, Eskandari Alley, Taleghani Ave</address>
        <city>Varamin</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>3371774031</zip>
        <telephone>+98 21 3627 2909</telephone>
        <email>varjavand@hotmail.com</email>
        <affiliation>Ministry of Cooperatives, Labor, and Social Affairs</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Wrestling club members The age range was between 18 and 20 years old.</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>20 years</agemax>
      <gender>Male</gender>
      <exclusion_criteria>Lack of supplements of L Citrulline Malate or arginine containing compounds</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group 1: L Citrulline Malate, Blood sampling for pretest immediately before starting the activity from each participate resistance and Supplements 3 grams per day for 60 days. endurance training program for 8 weeks and blood sampling at the end of the research. L Citrulline Malate Supplements of Hungarian Scitec company, 90 Kaspeln Citrulline Malate 3000 mg pro Portion</i_keyword>
      <i_keyword>Intervention group 2:  Only practice (The protocol is similar to 1) Resistance, endurance training program for 8 weeks.</i_keyword>
      <i_keyword>Intervention group 3: Only supplements (The protocol is similar to 1) Supplements 3 grams per day For 60 days. Blood sampling at the end of the research. L Citrulline Malate Supplements of Hungarian Scitec company, 90 Kaspeln Citrulline Malate 3000 mg pro Portion</i_keyword>
      <i_keyword>Control group 4: No training and supplementation</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Changes in NO and Comparison of the meanings at the beginning of the supplementary period and at the end after the supplement and sports activities are considered. Timepoint: Before the training period and after the supplement. Method of measurement: Special kit.</prim_outcome>
      <prim_outcome>Changes in GH and Comparison of the meanings at the beginning of the supplementary period and at the end after the supplement and sports activities are considered. Timepoint: Before the training period and after the supplement. Method of measurement: Special kit.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>IAU, Varamin</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2018-05-22</approval_date>
        <contact_name>Ethics Committee: Islamic Azad University of Varamin Pishva</contact_name>
        <contact_address>Naghshe jahan Pishva Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
