IRCT20180425039418N4 IRCT 2019-01-25 Zahedan University of Medical Sciences Evaluation of effectiveness of Sertraline and supportive psychotherapy on anxiety and depression level Evaluation of effectiveness of Sertraline and supportive psychotherapy on anxiety and depression level of Leukemia patient referring to clinic of Ali-ibn-Abitaleb Hospital in Zahedan 2018-12-22 anticipated 60 Complete https://irct.ir/trial/35565 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The simple randomization that the patients with the definite diagnosis of leukemia who referred to the clinic of Ali-Ibn-Abitaleb Hospital, will be classified into two groups each with 30 people by the. 2-3 Condition 1: Major depression disorders. Condition 2: Anxiety. Intervention 1: First intervention group: In this group, 30 patients with the definite diagnosis of leukemia with the age range of 18 to 64 years old at the clinic of Ali-ibn-Abitaleb Hospital in Zahedan, will treated with the administration of the first dose of 50 mg Sertraline. However, the dosage will be increased to 200mg daily due to the lack of response. Intervention 2: Second intervention group: In this group, 30 patients with definite diagnosis of Parkinson disease and age domain of 18 to 64 years old at the clinic of Ali-ibn-Abitaleb Hospital in Zahedan, will be treated by 6 weeks supportive psychotherapy in which each session has the duration of 90 minutes. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no information yet