IRCT138812093451N1 IRCT 2011-01-02 Babol University Of Medical Scienses, Dental Material Center The clinical evaluation of Platelet-Rich Plasma effects on Free Gingival Graft's donor site wound healing The clinical evaluation of Platelet-Rich Plasma effects on Free Gingival Graft's donor site wound healing 2010-02-19 anticipated 20 Complete https://irct.ir/trial/3558 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment. N/A wound healing. Intervention 1: using growth factors (autogenous, 0.5 cc): injected around the wound by insulin syringe. Intervention 2: control group normal healing process without growth factor application.

public Bardia Vadiati

Babol University Of Medical Scienses

Babol Iran (Islamic Republic of) +98 11 1222 7667 dr.bardia_vad@yahoo.com Babol University Of Medical Scienses scientific Bardia Vadiati

Babol University Of Medical Scienses

Babol Iran (Islamic Republic of) +98 11 1222 7667 dr.bardia_vad@yahoo.com Babol University Of Medical Scienses Iran (Islamic Republic of) Inclusion criteria: age 20 to 45 years old, need to bilateral (left and right) Free Gingival Graft for loss of attached gingiva or high frenum or shalloe vestibular depth, Recipient site has to be about 2 cm Exclusion criteria: presence of Systemic diseases or life style elements that impact on healing process such as diabetes mellitus, Immune system diseases, history of alcohol use, healing disorders, addiction, smoking or no cooperation, abnormal CBC or blooding time 20 years 45 years Both S00.5 Superficial injury of lip and oral cavity Treatment - Drugs N/A using growth factors (autogenous, 0.5 cc): injected around the wound by insulin syringe control group normal healing process without growth factor application. Wound healing. Timepoint: 2,4,7,14 days and second month after the surgery. Method of measurement: landry healing scale. Pain. Timepoint: days 2, 4, 7, 14 after surgery. Method of measurement: Visual Analogue Scale. Tissue thickness. Timepoint: before intervention and 2 months after surgery. Method of measurement: with periodontal probe and in milimeter. Babol University Of Medical Scienses, Dental Material Center Approved 2010-04-20 Babol University Of Medical Scienses Ethics committee Babol University Of Medical Scienses Babol Iran (Islamic Republic of)