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IRCT20181104041542N1 IRCT 2019-01-18 Esfahan University of Medical Sciences Comparison of the Effectiveness of Lidocaine and Lidocaine-Ketoroal Mixture on Mandible Anesthesia Comparative Evaluation of the effect of lidocaine-ketorolac mixture and lidocaine on Inferior Alveolar Nerve Block anesthesia in patients with irreversible pulpitis 2019-02-01 anticipated 80 Complete https://irct.ir/trial/35623 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Randomization description: Patients are Selected by Convenience Sampling and Disturbed into Case and Control Group by Random Numbers, Blinding description: In this study, conventional and changed anesthetic cartridge will be divided and numbered to two groups by an operator.The cartridges will be given to researcher.The researcher who doesn't know type of the cartridges will give them to dentist who wants to do the research.Finally by the permission of patients the research will be done. 3 Irreversible Pulpitis. Intervention 1: Intervention group: After informed contest, the initial anesthetic substance which is lidocaine HCL 2% with epinephrine 1:100,000, will be injected.After that, the studied anesthetic substance (0.8 mL of lidocaine HCL 2% with epinephrine 1:100,000 + 1ml of Ketorolac 30mg/ml) will be injected.Root canal treatment will have started after numbness of lower lip.The patient has been instructed to report the pain on the index if he/she feels any pain. Intervention 2: Control group: On this group, the second injection has normal saline instead of Ketorolac. Other steps are the same as intervention group. Yes - There is a plan to make this available What will be shared: Individual patients data after unidentification and the information of the main outcome is available. When: 6 months after the results are published To whom: Researchers working in academic institutions and research centers related to dentistry Conditions: Access to data and documentation is for study purposes only and is not subject to change or analysis Where to obtain: Vice-Chancellor's Office for Research, Isfahan Dentistry School How to obtain: Initially, the relevant scientific evidence and the reasons for the need for data will be provided to the Office of the Vice-Chancellor of Research and after the documents are presented, they will decide. Comments:
public Hessomoddin Faghihian
Isfahan Dentistry School, Sofeh St.
Isfahan Iran (Islamic Republic of) 8174673461 +98 36516128 hesamfgh95@gmail.com Esfahan University of Medical Sciences scientific Reyhaneh Faghihian
Department of Pediatric Dentistry, Isfahan Dentistry School, Sofeh St.
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3263 8163 r.faghihian@dnt.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) Patients Suffered from Irreversible Pulpitis in Their Lower Mandibular Molars Patients should be Considered ASA I or II 18 years 65 years Both Patients who are nursing or lactating during the study patients suffered from mental or physical disability patients who are allergic to NSAIDs patients who are using medicine during the study Treatment - Drugs Treatment - Drugs Intervention group: After informed contest, the initial anesthetic substance which is lidocaine HCL 2% with epinephrine 1:100,000, will be injected.After that, the studied anesthetic substance (0.8 mL of lidocaine HCL 2% with epinephrine 1:100,000 + 1ml of Ketorolac 30mg/ml) will be injected.Root canal treatment will have started after numbness of lower lip.The patient has been instructed to report the pain on the index if he/she feels any pain. Control group: On this group, the second injection has normal saline instead of Ketorolac. Other steps are the same as intervention group. Mandibular Molar Pain. Timepoint: Prior to intervention and After anesthetic injection during root canal treatment. Method of measurement: Heft-Parker's Visual Analogue Scale. Esfahan University of Medical Sciences Approved 2018-10-24 Ethics committee of Isfahan University of Medical Sciences Building No. 4, Isfahan University of Medical Sciences, Hezar Jarib St Isfahan Isfehan Iran (Islamic Republic of)