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IRCT20131218015860N5 IRCT 2019-03-10 Shahid Beheshti University of Medical Sciences Evaluation of topical Costus sp. preparation efficacy in treatment of neuropathy in cancer patients Evaluation of topical Costus sp. preparation efficacy in treatment of taxane induced peripheral neuropathy in cancer patients : a pilot study and a randomised controlled trial 2017-11-22 anticipated 50 Complete https://irct.ir/trial/36129 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: simple randomization: The numbers from 1 to 50 is written on 50 papers and placed inside a bag. Each time a patient enters the study according to entry criteria, a paper is removed from the bag and the number that is wirtten on the paper will be the number of intervention medication (which can be a Costus sp ointment or placebo), Blinding description: Costus sp and placebo was coded, patient and researcher were blind. 3 Neoplastic (malignant) related neuropathy. Intervention 1: Intervention group: cancer patients with taxane induced peripheral neuropathy, receiving ointment of Coctus sp, 1 mg three times daily for four weeks. Intervention 2: Control group: cancer patients with taxane induced peripheral neuropathy, receiving ointment of placebo, 1 mg three times daily for four weeks. Yes - There is a plan to make this available What will be shared: Demographic data and the result of the clinical trial When: 6 month later To whom: Researchers Conditions: After publication of the extracted article of the clinical trial Where to obtain: Sending Email to the researchers How to obtain: Sending the request via the email Comments:
public Dr. Ghazaleh Heydarirad
Shams Alley, Vali-e-Asr Street, Shahid Beheshti University of Medical Sciences
Tehran Iran (Islamic Republic of) 1516745811 +98 21 8877 3521 ghazalrad@yahoo.com Shahid Beheshti University of Medical Sciences scientific Dr. Ghazaleh Heydarirad
Shams Alley, Vali-e-Asr Street, Shahid Beheshti University of Medical Sciences
Tehran Iran (Islamic Republic of) 1516745811 +98 21 8877 3521 ghazalrad@yahoo.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Patients with cancer Patients undergoing chemotherapy or Complete chemotherapy in the last two months Patients with complained of neuropathy whose neuropathy is due to chemotherapy with taxane drugs Having symptoms of peripheral neuropathy in all four organs Having at least B grade based on the PNQ questionnaire Having at least 18 years and maximum 80 years 18 years 80 years Both diabetes renal failure Brain metastasis Carpal tunnel syndrome G62.0 Drug-induced polyneuropathy Treatment - Drugs Placebo Intervention group: cancer patients with taxane induced peripheral neuropathy, receiving ointment of Coctus sp, 1 mg three times daily for four weeks Control group: cancer patients with taxane induced peripheral neuropathy, receiving ointment of placebo, 1 mg three times daily for four weeks Severity of neuropathy based on patient's statements. Timepoint: 14, 21 and 28 days after interference. Method of measurement: Neuropathy Severity Scale questionnaire. Score of "The Cancer Neuropathy Scale". Timepoint: The weeks of 0 and 4 after treatment. Method of measurement: The Cancer neuropathy Scale questionnaire. Shahid Beheshti University of Medical Sciences Approved 2018-01-07 Ethics Committee on Biomedical Research of Shahid Beheshti University of Medical sciences Shahid Beheshti University of Medical sciences, Daneshju Blv. Tehran Tehran Iran (Islamic Republic of)