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IRCT20181112041620N1 IRCT 2019-03-12 Tehran University of Medical Sciences Effect of cyclosporine on hair loss of lichen planus Comparison of the simultaneous effect of oral administration of clobetasol lotion and cyclosporine with the clobetasol lotion alone in the treatment of lichen plano pilaris 2018-09-01 anticipated 40 Complete https://irct.ir/trial/36155 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: To conduct this research, referrals to Razi Hospital in Tehran who have Lpp disease, diagnosed as one month old and ranged from 15 to 70 years old, were randomly assigned 40 individuals individually And by hiding the drug using the spss analysis software, Blinding description: In this research, the method of double-blind study was used and the patients and primary investigators of the questioner were completely unaware of the treatment method. 3 Lichen planopilaris. Intervention 1: A lotion of clobetasol as a nosebleed topical steroid once at 30 drops for at least six months. Intervention 2: Oral ciclosporin at a dose of 1 to 3 mg / kg daily plus 30 drops of topical clobetasol lotion every night for 6 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is After completing the research and publication of the related article, a plan for publication will probably be announced
public Ensiyeh Yousefi Abdolmaleki
Tehran Province, Tehran, District 12, Islamic University of Wahdat-e-Islami St.
Tehran Iran (Islamic Republic of) 11111-11111 +98 21 5560 9951 ensiyehyousefi@gmail.com Tehran University of Medical Sciences scientific Dr. Vahidesadat Lajevardi
Tehran - Vahdat Islami St. - Islamic Unity Square - Razi's Death Row - Razi Skin Specialist Hospital
Tehran Iran (Islamic Republic of) ۱۱۹۹۶۶۳۹۱۱ +98 21 5563 0174 razihospital@sina.tums.ac.ir Tehran University of Medical Sciences Iran (Islamic Republic of) Patients with lichen plano pilaris disease at Razi Hospital Age limits of 15 to 40 years 15 years 40 years Both Must be at least one month from the initial referral of these patients to the hospital L67 Hair color and hair shaft abnormalities Placebo Placebo A lotion of clobetasol as a nosebleed topical steroid once at 30 drops for at least six months Oral ciclosporin at a dose of 1 to 3 mg / kg daily plus 30 drops of topical clobetasol lotion every night for 6 months Plano Polaris's patients percentage. Timepoint: 60days. Method of measurement: Therapeutic questions from the patient. Patients may also experience minor problems such as scaling and atrophy due to drug use. Timepoint: 30 days. Method of measurement: Random selection of patients and therapist's questions. Tehran University of Medical Sciences Approved 2018-08-21 Tehran University of Medical Sciences Mulla Sadra Street- North Shirazi Ave. - East Saeb Street - No. 216 Tehran Tehran Iran (Islamic Republic of)