]>
IRCT20181216041991N1 IRCT 2019-01-23 Shahid Beheshti University of Medical Sciences Comparison of the effect of oral Oxycodone versus intravenous Ketorolac on post laparoscopic cholecystectomy pain Comparison of the effect of oral Oxycodone versus intravenous Ketorolac on post laparoscopic cholecystectomy pain 2019-01-10 anticipated 60 Complete https://irct.ir/trial/36229 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Sealed envelop method, Blinding description: Researcher open the pockets confidentially to learn the patient's group. The patients pain scores and other results are documented by an unaware personnel. 3 The effect of medications on post laparoscopic cholecystectomy pain. Intervention 1: Intervention group: In the first group patients receive 30 mg of oral oxycodone before anesthesia induction. Intervention 2: Intervention group: In the second group before anesthesia induction patients receive 30 mg of intravenous ketorolac dissolved in 100 ml normal saline in 30 minute. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The research group has not agreed on a consensus yet.
public Masoud Nashibi
Loghman Hospital, Kamali street, South Kargar street, Tehran, Iran
Tehran Iran (Islamic Republic of) 1333635445 +98 21 5542 4040 masoudnashibi@sbmu.ac.ir Shahid Beheshti University of Medical Sciences scientific Masoud Nashibi
Loghman Hospital, Kamali street, South Kargar street, Tehran, Iran
Tehran Iran (Islamic Republic of) 1333635445 +98 21 5542 4040 masoudnashibi@sbmu.ac.ir Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Patients candidate for laparoscopic cholecystectomy Age between 18-65 year 18 years 65 years Both No history of drug abuse No history of psychologic disease No allergy to studied drugs No pregnancy and lactation No clinical sign due to sepsis or other inflammatory disease No history of liver and renal failure No history of GI bleeding No history of coagulopathies No history of sign of neuropathy No diagnosis of gangrenous cholecystitis No diagnosis of generalized peritonitis Treatment - Drugs Treatment - Drugs Intervention group: In the first group patients receive 30 mg of oral oxycodone before anesthesia induction. Intervention group: In the second group before anesthesia induction patients receive 30 mg of intravenous ketorolac dissolved in 100 ml normal saline in 30 minute. Postoperative pain. Timepoint: 1,2,4,6,12 hours postoperative. Method of measurement: Numerical rating Scale;The NRS is a 10 cm horizontal bar which is divided to 0-10 pieces. Respondent selects a whole number (0–10 integers) that best reflects the intensity of his/her pain. Number zero eqauals no pain, while number ten means unbearable pain. Shahid Beheshti University of Medical Sciences Approved 2019-01-06 Ethics committee of Shahid Beheshti University of Medical Sciences 7th Floor, Bldg No.2 SBUMS, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)