IRCT138812223550N1 IRCT 2009-09-23 Tehran University of Medical Sciences The effect of olive oil rich diet consumption on serum omentin concentration The effect of olive oil rich diet consumption on serum omentin concentration in overweight women 2009-09-23 anticipated 16 Complete https://irct.ir/trial/3644 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Basic scienece. 2 Condition 1: Serum omentin concentration in owerweight women. Condition 2: Overweight. Intervention 1: Diet rich in olive oil with composition:51% carbohydrate.15% protein. 34% fat.8% SFA.10% PUFA.16% MUFA for six weeks. Intervention 2: Common diet with composition:51% carbohydrate.15% protein. 34% fat.16% SFA.10% PUFA.8% MUFA for six weeks.

public Fahimeh Haghighatdoost

Faculty of Public health,Tehran University of Medical Sciences, Enghelab square

Tehran Iran (Islamic Republic of) +98 31 1230 4119 f_haghighatdoost@yahoo.com Faculty of Public health,Tehran University of Medical Sciences scientific Dr. Mohammad Javad Hosseinzadeh

Nutrition and biochemistry group, faculty of Public health,tehran University of Medical Sciences, Enghelab square

Tehran Iran (Islamic Republic of) +98 21 8895 1395 hosseinzadeh.mdphd@yahoo.com ; mjha3@yahoo.com Nutrition and biochemistry group, faculty of Public health,Tehran University of Medical Sciences Iran (Islamic Republic of) Inclusion Criteria: married women age: 20-50-year, BMI between 25-29/9, absence of clinical signs or symptoms of coronary artery disease, diabetes, metabolic diseases, arthritis, lupus, GI diseases, hypertension, any kind of infection, trauma, thyroid diseases, without history of using drugs, such as anti- hypertensive, anti hyperlipidemia, anti-inflammatory, anti diabetic agents, drugs for weight reduction, OCP, corticosteroids, not pregnancy and lactation, not smoking. Exclusion criteria: pregnancy, breast feeding, presence of any disease and use of drugs that mentioned above, don’t follow the diets 20 years 50 years Female - E66.0 - Obesity due to excess calories Treatment - Drugs Treatment - Drugs Diet rich in olive oil with composition:51% carbohydrate.15% protein. 34% fat.8% SFA.10% PUFA.16% MUFA for six weeks Common diet with composition:51% carbohydrate.15% protein. 34% fat.16% SFA.10% PUFA.8% MUFA for six weeks Serum omentin concentration. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Elisa kit. Plasma adiponectin concentration. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Elisa kit. C- reactiv protein. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Elisa kit. Insulin. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Elisa kit. Fasting blood glucose. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Elisa kit. Lipid profile(cholestrol-triglicerid-HDL-LDL). Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Elisa kit. Weight. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Seca digital scale. Body mass index. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Calculate. Body fat mass. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Bioempedance device. Waist and hip circumference. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Meter. Waist to hip ratio. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Calculate. Blood pressure. Timepoint: At the beginning and at the end of phase one and two. Method of measurement: Manometer. Tehran University of Medical Sciences Approved Tehran University of Medical Sciences Ghods Ave. Tehran Iran (Islamic Republic of)