<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20190105042244N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2019-03-02</date_registration>
      <primary_sponsor>Ahvaz University of Medical Sciences</primary_sponsor>
      <public_title>The effect of resistance exercise on serum testosterone levels in middle aged men</public_title>
      <acronym></acronym>
      <scientific_title>Study of the effect of resistance exercise on serum testosterone levels, severity signs of aging and quality of life in middle-aged men with late-onset hypogonadism</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2018-12-31</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>60</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/36902</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Supportive, Other design features: The study sample consisted of 60 available patients who entered the study according to the criteria of inclusion and then divided into two groups of test and control by random allocation method, Randomization description: The method of assigning samples to the experimental and control groups was randomized and random blocked blocks with block size 6(Using the table for random permissions).A randomized list is provided by a statistician.According to a randomized list, it is allocated by a person outside the study according to the codes for each disease that is included in the study.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Condition 1: late-onset hypogonadism. Condition 2: late-onset hypogonadism.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: For men in the intervention group, serum testosterone levels, severity of aging symptoms and quality of life were measured first, and then the intervention group performed resistance exercise for one month. At the end of the intervention, the group again tested for testosterone levels, severity of aging symptoms and quality Life .At the end, the data before and after the intervention are compared with each other and compared to the control group. Intervention 2: Control group:For men in the control group, serum testosterone level, severity of aging symptoms and quality of life were measured first. The group then continued their lifestyle for one month. After the study was completed, the group again tested the level of testosterone, severity of aging symptoms and quality of life, At the end, the data before and after the study are compared with each other and compared to the  intervention group.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
The data of the participating participants will be encrypted and will be published with the privacy of the patient and the confidentiality of the information.

When:
The date of access to the data is six months after the publication of the results

To whom:
Only available to scholars working in academic and academic institutions

Conditions:
The requirements for access to data include the sending of documents relating to the applicant's membership in academic and academic institutions, and the applicant is authorized to use this data in order to document for subsequent studies.

Where to obtain:
You can use the email address to access the information
1.Gheibizadeh-m@ajums.ac.ir
2.Hamid_taghipoor@yahoo.com

How to obtain:
The applicant will send the data to him at least one month later by sending valid credentials to members of the academic and research institutes at the email address of the author.

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Mahin Gheibizadeh</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Golestan Highway - Jundishapur University of Medical Sciences</address>
        <city>Ahvaz</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>6135-15794</zip>
        <telephone>+98 61333738394</telephone>
        <email>Gheibizadeh-m@ajums.ac.ir</email>
        <affiliation>Ahvaz University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Diniar Khazaali</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Golestan Highway - Ahvaz Jundishapur University of Medical Sciences</address>
        <city>Ahvaz</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>61357-15794</zip>
        <telephone>+98 61 3222 2922</telephone>
        <email>khazaeli-d@ajums.ac.ir</email>
        <affiliation>Ahvaz University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Married
Age 65-40 years old
The score obtained from the aging mals symptom questionnaire is greater than 27
Diagnosis of late men's hypogonadism based on serum testosterone level</inclusion_criteria>
      <agemin>40 years</agemin>
      <agemax>65 years</agemax>
      <gender>Male</gender>
      <exclusion_criteria>Acute mental illness and not having acceptable general health
Physical Limit for Exercise 
Tobacco and alcohol consumption
Perform regular resistance training in the last three months
Use of ergogenic supplements before the study</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>E29.1</hc_code>
      <hc_code>E29.1</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Testicular hypofunction</hc_keyword>
      <hc_keyword>Testicular hypofunction</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Lifestyle</i_code>
      <i_code>Lifestyle</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: For men in the intervention group, serum testosterone levels, severity of aging symptoms and quality of life were measured first, and then the intervention group performed resistance exercise for one month. At the end of the intervention, the group again tested for testosterone levels, severity of aging symptoms and quality Life .At the end, the data before and after the intervention are compared with each other and compared to the control group.</i_keyword>
      <i_keyword>Control group:For men in the control group, serum testosterone level, severity of aging symptoms and quality of life were measured first. The group then continued their lifestyle for one month. After the study was completed, the group again tested the level of testosterone, severity of aging symptoms and quality of life, At the end, the data before and after the study are compared with each other and compared to the  intervention group</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Serum total testosterone. Timepoint: Before and after intervention. Method of measurement: Elisa biochemical assay.</prim_outcome>
      <prim_outcome>Severe aging symptoms. Timepoint: Before and after intervention. Method of measurement: Using aging male Symptoms Questionnaire.</prim_outcome>
      <prim_outcome>Quality of Life. Timepoint: Before and after intervention. Method of measurement: Measured using SF-36 questionnaire.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Ahvaz University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2018-12-29</approval_date>
        <contact_name>Ethics Committee of Ahwaz University of Medical Sciences</contact_name>
        <contact_address>Golestan Highway. Ahvaz Jundishapur University of Medical Sciences Ahvaz Khouzestan Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
