]>
IRCT20140215016582N3 IRCT 2019-07-03 Vice Chancellor for Research and Technology, Hamedan University of Medical Science Effect of titanuim oxide coating on streptococcus mutans adhesion Evaluation of streptococcus mutans adhesion on stainless steel orthodontic wire caoted with titanuim oxide in orthodontic patients 2019-08-22 anticipated 68 Complete https://irct.ir/trial/37098 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this study, a block randomization method is used. Group name (A, B, C, D) is written on the 4 cards and the first patient chooses one of them. The next patient chooses one of the three remaining cards, the next patient will be assigned one of the two cards and the last card allocated to the fourth patient, Blinding description: Participants are unaware of wires(coated or non-coated) located in the upper or lower jaw, and also, the person who evaluates the outcome is blinded. N/A Streptococcus mutans adhesion to orthodontic wire. Intervention 1: Intervention group : In Group A, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly located in the upper or lower jaw and after one week exit from mouth. Intervention 2: Intervention group: In Group B, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly located in the upper or lower jaw and after two weeks exit from mouth. Intervention 3: Intervention group: In group C, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly placed in the upper or lower jaw and exit after three weeks from mouth. Intervention 4: Intervention group: In Group D, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly placed in the upper or lower jaw and exit after four weeks from mouth. Intervention 5: Control group: The control group is uncoated orthodontic wires 0.018 stainless steel that is placed in the opposite jaw in front of the intervention group. Yes - There is a plan to make this available What will be shared: Individual data including demographic characteristics and original outcome information are shared. When: Start the access period 6 months after printing the results To whom: Researchers working in academic and scientific institutes and dental material industry Conditions: Unidentifiable information will not be provided due to the type of consent given to patients and the obligation of the investigator to comply with ethical requirements. Where to obtain: Ziba Banisafar, Corresponding author, zbanisafar@yahoo.com Vahid Mollabashi, First authorÙˆ mollabashi@umsha.ac.ir How to obtain: After 6 month of result publication through electronic E-Mail of corresponding author and complete introduction and mention the goal from having the documentation, related file is available to the applicant. Comments:
public Ziba Banisafar
Shahid Fahmideh Ave.,Hamadan University of Medical Science
Hamadan Iran (Islamic Republic of) 65178-38677 +98 81 3838 1059 zbanisafar@yahoo.com Hamedan University of Medical Sciences scientific Ziba Banisafar
Shahid Fahmideh Ave., Hamadan University of Medical Science
Hamadan Iran (Islamic Republic of) 65178-38677 +98 81 3838 1059 zbanisafar@yahoo.com Hamedan University of Medical Sciences Iran (Islamic Republic of) Patients referring to Hamadan Dental School Age ranged 12-25 years old Non-use of antibacterial mouthwashes and antibiotics during treatment Non-use of interarch elastics,chain,O-ring and open coil during treatment 12 years 25 years Both The presence of systemic diseases such as : diabetes, AIDS and consumers of immunosuppressive drugs Pregnancy Smoking The presence of dental missing, syndroms and craniofacial anomalies Prevention Prevention Prevention Prevention Prevention Intervention group : In Group A, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly located in the upper or lower jaw and after one week exit from mouth. Intervention group: In Group B, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly located in the upper or lower jaw and after two weeks exit from mouth. Intervention group: In group C, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly placed in the upper or lower jaw and exit after three weeks from mouth. Intervention group: In Group D, the orthodontic wires 0.018 stainless steel coated with 100 nm titanium oxide layer are randomly placed in the upper or lower jaw and exit after four weeks from mouth. Control group: The control group is uncoated orthodontic wires 0.018 stainless steel that is placed in the opposite jaw in front of the intervention group. Streptococcus mutans adhesion to orthodontic wires. Timepoint: Bacterial counting in 4 groups with 1 to 4 weeks interval. Method of measurement: Colony count. Evaluation of anti-adherent property of coated wire during the time. Timepoint: Aftar 1 week , 2 weeks, 3 weeks, 4 weeks. Method of measurement: Colony count. Vice Chancellor for Research and Technology, Hamedan University of Medical Science Approved 2019-01-26 Ethics committee of Hamadan University of Medical Sciences Shahid Fahmide Ave., Hamadan university of Medical science Hamadan Hamadan Iran (Islamic Republic of)