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IRCT20100124003146N6 IRCT 2019-03-10 Kashan University of Medical Sciences Investigating the effect of essential oil of thyme on oral microbial burden in mechanical ventilated ICU patients. Investigating the effect of essential oil of thyme on oral microbial burden in mechanical ventilated ICU patients. 2019-01-21 anticipated 90 Complete https://irct.ir/trial/37111 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients with inclusion criteria were randomly divided into three groups.Equal number of sample was allocated to each group using a randomized block method, Blinding description: Because participating patients have low level of consciousness and are ventilated, are not aware of the type of intervention (mouthwash) and are blind. On the other hand, the person who analyzes the culture is not aware of the type of mouthwash used. 3 oral thrush. Intervention 1: intervention group1: Mouthwash group with Thyme essential oil. The mouthwash, which is made by Barij essence company is made up of 10% glycidic solution, will be used twice a day (morning and night) for patients.So that the entire level of the mouth, gums, pharynx and tooth surfaces are swabbed for 6 minutes with 5 cc of solution.At the end of the mouthwash, the solution is removed from the mouth by suction (a sterile catheter without previous use). Intervention 2: Intervention group2: Mouthwash group with chlorohexidine 0.2% of Iran's Health Generation Company. So that the entire level of the mouth, gums, pharynx and tooth surfaces are swabbed for 6 minutes with 5 cc of solution.At the end of the mouthwash, the solution is removed from the mouth by suction (a sterile catheter without previous use). Intervention 3: Control group: The normal saline will be used.So that, the entire level of the mouth, gums, pharynx and tooth surfaces are swabbed for 6 minutes with 5 cc of solution.At the end of the mouthwash, the solution is removed from the mouth by suction (a sterile catheter without previous use). Yes - There is a plan to make this available What will be shared: the results related to the main outcome will be distributed. When: after the publication of the article To whom: all people Conditions: data will be confidential Where to obtain: aziz-es@kaums.ac.ir How to obtain: the process will be announced later. Comments:
public Dr Esmail Azizi-Fini
5Th Kilometer Qotb Ravandi blouvar.kashan university of medical sciences
kashan Iran (Islamic Republic of) 8715981151 +98 31 5554 0021 azizi-es@kaums.ac.ir Kashan University of Medical Sciences scientific Dr Esmail Azizi-Fini
5th kilometer Qotb Ravandi Blouvar
kashan Iran (Islamic Republic of) 8715981151 +98 31 5554 0021 azizi-es@kaums.ac.ir Kashan University of Medical Sciences Iran (Islamic Republic of) All the patients under the mechanical ventilation in intensive care units no limit no limit Both Patients with no prohibition for mouthwash Patients with no sensitivity to thyme B37.0 Candidal stomatitis Treatment - Drugs Treatment - Drugs Placebo intervention group1: Mouthwash group with Thyme essential oil. The mouthwash, which is made by Barij essence company is made up of 10% glycidic solution, will be used twice a day (morning and night) for patients.So that the entire level of the mouth, gums, pharynx and tooth surfaces are swabbed for 6 minutes with 5 cc of solution.At the end of the mouthwash, the solution is removed from the mouth by suction (a sterile catheter without previous use). Intervention group2: Mouthwash group with chlorohexidine 0.2% of Iran's Health Generation Company. So that the entire level of the mouth, gums, pharynx and tooth surfaces are swabbed for 6 minutes with 5 cc of solution.At the end of the mouthwash, the solution is removed from the mouth by suction (a sterile catheter without previous use). Control group: The normal saline will be used.So that, the entire level of the mouth, gums, pharynx and tooth surfaces are swabbed for 6 minutes with 5 cc of solution.At the end of the mouthwash, the solution is removed from the mouth by suction (a sterile catheter without previous use). Oral microbial load. Timepoint: before using mouthwash and seven days after the intervention. Method of measurement: oral culture. Anti bio-gram. Timepoint: before and seven days after intervention. Method of measurement: sample of oral culture. Kashan University of Medical Sciences Approved 2019-01-21 Ethics committee of Kashan University of Medical Sciences 5th kilometer Qotb Ravandi blouvar kashan Isfehan Iran (Islamic Republic of)