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IRCT201301263664N9 IRCT 2013-03-16 Nutritional Reseach Center of Tabriz University of Medical Sciences Effects of fenugreek seeds consumption on metabolic status,serum adiponectin,Hs-CRP & ICAM-1(Intercellular Adhesion Molecule-1) levels in type2 diabetic patients Effects of fenugreek seeds consumption on metabolic status,serum adiponectin,Hs-CRP & ICAM-1(Intercellular Adhesion Molecule-1) levels in type2 diabetic patients 2013-04-04 anticipated 90 Complete https://irct.ir/trial/3753 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive. 2-3 Diabet Mellitus. Intervention 1: 10 G of Powdered Fenugreek Seeds Twice a Day - 8 Weeks. Intervention 2: 5 G Starch Twice a Day- 8 Weeks.
public Mina Malekiyan
Nutrition School, Attare Neishaboori Avenue, Golgasht Street
Tabriz Iran (Islamic Republic of) +98 42 6223 0227 mina.malekiyan@yahoo.com Tabriz University of Medical Sciences scientific Mina Malekiyan
Nutrition School, Attare Neishaboori Avenue, Golgasht Street
Tabriz Iran (Islamic Republic of) +98 42 6223 0227 mina.malekiyan@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Inclusion Criteria: Volunteered to Participate in The Sudy ؛At Least 6 Months History of Dabetes ؛Use of Blood Sugar Lowering Drugs؛BMI ≤ 35, Women 30-50 Years and Men Age 30-60، Exclusion Criteria: Pregnancy and lactation ؛Liver Disease،Kidney،Heart Disease،Thyroid Disease،Inflammatory and ... ؛Patients treated with Insulin،Lipid Lowering Drugs، Diuretics،and Use of Detary Supplements،Vitamins and Minerals ؛Hormone Therapy ؛Smoking؛Change in Dose of Oral Hypoglycemic Drugs During The Study ؛Taking Antioxidant Supplements at Least Three Months before the Study and During The Study؛ at Least 6 Weeks Prior to The Intervention Diet Weight Loss 30 years 60 years Both E11 Non-Insulin-Dependent Diabetes Mellitus Treatment - Other Placebo 10 G of Powdered Fenugreek Seeds Twice a Day - 8 Weeks 5 G Starch Twice a Day- 8 Weeks FBS. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotometer. HbA1C. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With HPLC. Level of Serum Insulin. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With ELISA. HOMA-IR. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Calculated According to The Formula. Total Cholestrol. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotometer. LDL-C. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Calculated According to The Friedwald Formula. HDL-C. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Immunoturbidimetry. TG. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotometer. Level of Serum Adiponectin. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With ELISA. Level of Serum Hs-CRP. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Immunoturbidimetry. Level of Serum ICAM-1. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With ELISA. Vice chancellor for research, Tabriz University of Medical Sciences Nutritional Reseach Center of Tabriz University of Medical Sciences Vice chancellor for research, Tabriz University of Medical Sciences Approved 2013-03-02 The Research Ethics Committee of Tabriz University of Medical Sciences Attar Neishaboori Avenue, Golgasht Atreet Tabriz Iran (Islamic Republic of)