IRCT20190224042815N1 IRCT 2019-07-24 Tehran University of Medical Sciences Evaluating the effect of thiamine on delirium Evaluating the preventive effect of vitamin B1 on Delirium in critically ill patients 2640-05-18 anticipated 90 Pending https://irct.ir/trial/37797 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Randomization unit: Block randomization Randomization tool: SAS statistical software, sealed envelope How to create a random sequence: SAS statistical software, Blinding description: Use non-transparent sealed envelopes with random sequences. 2-3 Post operation. Intervention 1: "Intervention Group" : 'The group receiving thiamine hydrochloride 50 mg/ml ampule Ratiopharm GmbH company is injected at a daily dose of 200 mg (4 ampulla ) in serum for three days. Intervention 2: "Control group": The group receiving placebo (four CC of normal saline ) is injected in the same syringe as the intervention group in the serum for three days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is After the study, it will be decided upon. "There is no further information."